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Merck
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문서

V0882

Sigma-Aldrich

D-Val-Leu-Lys 4-nitroanilide dihydrochloride

plasmin substrate

동의어(들):

D-Val-Leu-Lys-pNA dihydrochloride, D-Valyl-L-leucyl-L-lysine 4-nitroanilide dihydrochloride

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모든 사진(1)

About This Item

실험식(Hill 표기법):
C23H38N6O5 · 2HCl
CAS Number:
62354-43-2
Molecular Weight:
551.51
MDL number:
MFCD00077899
UNSPSC 코드:
12352204
PubChem Substance ID:
24900701
NACRES:
NA.32

분석

≥98% (TLC)

형태

powder

solubility

water: 50 mg/mL, clear, colorless to yellow

저장 온도

−20°C

SMILES string

Cl.Cl.CC(C)C[C@H](NC(=O)[C@H](N)C(C)C)C(=O)N[C@@H](CCCCN)C(=O)Nc1ccc(cc1)[N+]([O-])=O

InChI

1S/C23H38N6O5.2ClH/c1-14(2)13-19(28-23(32)20(25)15(3)4)22(31)27-18(7-5-6-12-24)21(30)26-16-8-10-17(11-9-16)29(33)34;;/h8-11,14-15,18-20H,5-7,12-13,24-25H2,1-4H3,(H,26,30)(H,27,31)(H,28,32);2*1H/t18-,19-,20+;;/m0../s1

InChI key

VESQMNNSPPEOSZ-ZLARAOTRSA-N

유사한 제품을 찾으십니까? 방문 제품 비교 안내

애플리케이션

D-Val-Leu-Lys 4-nitroanilide dihydrochloride has been used as a chromogenic substrate to determine the formation of plasmin from plasminogen in amidolytic activity assay and plasminogen activating assay.

픽토그램

Health hazardExclamation mark
GHS08,GHS07

신호어

Warning

유해 및 위험 성명서

H302 + H312 + H332,H315,H319,H335,H361

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 3

표적 기관

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

개인 보호 장비

dust mask type N95 (US), Eyeshields, Gloves

시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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이미 열람한 고객

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D-Val-Leu-Arg p-nitroanilide diacetate salt ≥95% (HPLC)

Sigma-Aldrich

V6258

D-Val-Leu-Arg p-nitroanilide diacetate salt

S Ueshima et al.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 7(5), 522-529 (1996-07-01)
Staphylokinase (SAK), produced by Staphylococcus aureus, induces fibrinolytic activity in circulation without systemic fibrinolytic activation. Since the effect of blood vessels on the activity of SAK has not yet been clarified, plasminogen activator (PA) activity of SAK in the presence
L C Petersen
European journal of biochemistry, 245(2), 316-323 (1997-04-15)
The two zymogens, plasminogen and pro-urokinase plasminogen activator (pro-uPA), constitute a system of reciprocal activation, since plasmin, generated by uPA-catalysed plasminogen activation, can activate pro-uPA to uPA. Two such zymogens, when mixed, will undergo autocatalytic, reciprocal activation resulting in generation
Genetic modification of the streptokinase gene to study the interaction of streptokinase with plasminogen.
S Lizano et al.
Developments in biological standardization, 85, 195-198 (1995-01-01)
K M Rippel et al.
Journal of dairy science, 87(8), 2344-2350 (2004-08-26)
The plasmin system native to bovine milk consists of the caseinolytic serine proteinase plasmin; its inactive zymogen, plasminogen; plasminogen activators; and inhibitors. Evidence in the literature indicates that whey proteins may inhibit plasmin activity, but there is very little mention
M Yamada et al.
Veterinary research communications, 21(2), 75-84 (1997-02-01)
An active fraction that accelerates plasminogen activation by tissue-type plasminogen activator (t-PA) was purified from a haemolysate of bovine erythrocytes. When the haemolysate was mixed with t-PA, it produced a 2- to 3-fold increase in plasminogen activation as measured by
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프로토콜

Enzymatic Assay of Plasmin with D-Val-Leu-Lys-p-Nitroanilide Dihydrochloride

Protocol for Enzymatic Assay of Plasmin with D-Val-Leu-Lys-p-Nitroanilide Dihydrochloride

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