분석
≥98% (HPLC)
형태
solid
분자량
(mass spec confirms mol. wt.)
색상
white
solubility
DMSO: soluble
저장 온도
2-8°C
SMILES string
N[C@@H](Cc1ccc(O)cc1)C(=O)N2Cc3ccccc3C[C@H]2CN[C@@H](Cc4ccccc4)C(=O)N[C@@H](Cc5ccccc5)C(O)=O
애플리케이션
TIPP-Ψ has been used as a positive control during the screening for delta-opioid receptor (DOR) modulators.
생화학적/생리학적 작용
Selective δ-opioid receptor antagonist.
제조 메모
TIPP-Ψ is soluble in DMSO.
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Acta pharmacologica Sinica, 29(4), 507-516 (2008-03-25)
To develop a universal high-throughput screening assay based on Galpha15/16- mediated calcium mobilization for the identification of novel modulators of Gprotein- coupled receptors (GPCR). In the present study, CHO-K1 or HEK293 cells were co-transfected with plasmids encoding promiscuous G-protein Galpha15/16
The Journal of pharmacology and experimental therapeutics, 298(1), 240-248 (2001-06-16)
A new class of highly selective delta-opioid receptor antagonists has been recently developed, termed the TIP(P) peptides. Two prototypical compounds in this class are TIPP (H-Tyr-Tic-Phe-Phe-OH) and a derivative, TIPP-psi (H-Tyr-Tic[CH2NH]-Phe-Phe-OH). Surprisingly, both TIPP and TIPP-psi demonstrated inhibition of adenylyl
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