T4192

Tyrphostin SU 1498

≥98%

• 동의어(들): (E)-N-(3″-Phenylpropyl)-α-cyano-3′,5′-diisopropyl-4′-hydroxycinnamamide
• 실험식(Hill 표기법): C₂₅H₃₀N₂O₂
• CAS Number: 168835-82-3
• Molecular Weight: 390.52
• MDL number: MFCD03453026
• UNSPSC 코드: 12352200
• PubChem Substance ID: 24900199

속성

• 분석: ≥98%
• 형태: solid
• 효능: 700 nM IC₅₀
• solubility: DMSO: soluble
• 저장 온도: −20°C
• SMILES string: CC(C)c1cc(\C=C(/C#N)C(=O)NCCCc2ccccc2)cc(C(C)C)c1O
• InChI: 1S/C25H30N2O2/c1-17(2)22-14-20(15-23(18(3)4)24(22)28)13-21(16-26)25(29)27-12-8-11-19-9-6-5-7-10-19/h5-7,9-10,13-15,17-18,28H,8,11-12H2,1-4H3,(H,27,29)/b21-13+
• InChI key: JANPYFTYAGTSIN-FYJGNVAPSA-N

설명

애플리케이션

Tyrphostin SU 1498 has been used as a VEGF inhibitor in mice¹.

생화학적/생리학적 작용

Potent and selective inhibitor of the VEGF receptor kinase, Flk-1. Very weak inhibitor of PDGFR-kinase, EGFR-kinase and HER-2 kinase.

제조 메모

Tyrphostin SU 1498 is soluble in DMSO.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H315,H319,H335
• 예방조치 성명서: P261 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves