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Merck
모든 사진(1)

문서

T3397

Sigma-Aldrich

Tylosin solution

solution, suitable for cell culture, BioReagent

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About This Item

CAS Number:
MDL number:
UNSPSC 코드:
12352207
PubChem Substance ID:
NACRES:
NA.76

product name

Tylosin solution, 8 mg/mL in 0.9% NaCl, 0.1 μm filtered, BioReagent, suitable for cell culture

Quality Level

무균

0.1 μm filtered

제품 라인

BioReagent

형태

solution

농도

8 mg/mL in 0.9% NaCl

기술

cell culture | mammalian: suitable

불순물

endotoxin, tested

색상

colorless to yellow

항생제 활성 스펙트럼

Gram-positive bacteria
mycoplasma

동작 모드

protein synthesis | interferes

저장 온도

2-8°C

SMILES string

O[C@H]([C@@H](O)C(O)=O)C(O)=O.CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O[C@H]3C[C@@](C)(O)[C@@H](O)[C@H](C)O3)[C@@H]([C@H]2O)N(C)C)[C@@H](CC=O)C[C@@H](C)C(=O)\C=C\C(C)=C\[C@@H]1CO[C@@H]4O[C@H](C)[C@@H](O)[C@@H](OC)[C@H]4OC

InChI

1S/C46H77NO17.C4H6O6/c1-13-33-30(22-58-45-42(57-12)41(56-11)37(52)26(5)60-45)18-23(2)14-15-31(49)24(3)19-29(16-17-48)39(25(4)32(50)20-34(51)62-33)64-44-38(53)36(47(9)10)40(27(6)61-44)63-35-21-46(8,55)43(54)28(7)59-35;5-1(3(7)8)2(6)4(9)10/h14-15,17-18,24-30,32-33,35-45,50,52-55H,13,16,19-22H2,1-12H3;1-2,5-6H,(H,7,8)(H,9,10)/b15-14+,23-18+;/t24-,25+,26-,27-,28+,29+,30-,32-,33-,35+,36-,37-,38-,39-,40-,41-,42-,43+,44+,45-,46-;1-,2-/m11/s1

InChI key

ICVKYYINQHWDLM-KBEWXLTPSA-N

관련 카테고리

일반 설명

Chemical structure: macrolide
Tylosin is a macrolide antibiotic, which comprises of a 16-member lactone ring. This solution is recommended for use at 1 mL/L.

애플리케이션

Tylosin solution has been used as an antimicrobial agent in antibiotic susceptibility minimal inhibitory concentration(MIC) of E. coli and S. aureus isolates. It has also been used as a component of Dulbecco′s modified Eagle′s (DMEM) medium for self-inactivating lentivirus production and skin fibroblast cultivation.

생화학적/생리학적 작용

Tylosin inhibits bacterial protein synthesis by binding to the large subunit 50S. It is effective against Gram-positive bacteria and mycoplasma and is used in veterinary medicine. It has been used to study implant site abscess prevention in cattle and Mycoplasma gallisepticum and Mycoplasma meleagridis infections.

포장

20ML

제조 메모

This product was formulated to contain 8 mg/ml tylosin in 0.9% sodium chloride.

저장 및 안정성

Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and keep upright to prevent leakage.

기타 정보

Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage.

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리 방문

Tools for characterizing bacterial protein synthesis inhibitors
Orelle C, et al.
Antimicrobial Agents and Chemotherapy, 57(12), 5994-6004 (2013)
Effects of a tylosin tartrate pellet added to cattle growth implants on the incidence of implant site abscesses
Zollers JrWG, et al.
The Protein Kinase Facts Book, 18(3), 258-261 (2002)
Cytosolic, but not matrix, calcium is essential for adjustment of mitochondrial pyruvate supply
Szibor M, et al.
Test, 295(14), 4383-4397 (2020)
EVALUATION OF THE EFFECT OF TYLOSIN (MACROLIDE ANTIBIOTICS) ON MURINE TOXOPLASMOSIS
Asgari Q, et al.
International Journal of Pharmaceutical Sciences and Research, 9(7), 2891-2896 (2018)
Frizzled 1 and Wnt1 as new potential therapeutic targets in the traumatically injured spinal cord
Gonzalez P, et al.
Cellular and Molecular Life Sciences, 80, 1-32 (2020)

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