SRP6027

UbcH5b human

recombinant, expressed in E. coli, ≥95% (SDS-PAGE)

• 동의어(들): UbcH
• CAS Number: 2026618-65-3
• UNSPSC 코드: 12352200
• NACRES: NA.32

속성

• 생물학적 소스: human
• 재조합: expressed in E. coli
• 분석: ≥95% (SDS-PAGE)
• 형태: liquid
• 분자량: 17.0 kDa
• 포장: pkg of 10 μg
• 농도: ~1.0 mg/mL
• 불순물: Endotoxin, tested
• NCBI 수납 번호: P62837
• 배송 상태: dry ice
• 저장 온도: −70°C
• 유전자 정보: human ... UB2D2(7322)

설명

일반 설명

E2 ubiquitin conjugating enzyme (UbcH5b), also called as ubiquitin conjugating enzyme E2D2 (UBE2D2), belongs to the active class of E2 ubiquitin conjugating enzymes, which also includes UbcH5A and UbcH5C. UbcH5b structure contains four N-terminal α-helices followed by four-stranded antiparallel β-sheet.

생화학적/생리학적 작용

E2 ubiquitin conjugating enzyme (UbcH5b) is a vital component of E3 complex SCFβ-TrCP and it plays an important role in phospho-IκBα ubiquitination. UbcH5b along with others members of active classes of E2 enzymes plays a vital role in degradation of many regulatory and abnormal proteins, including important human transcription factors, such as p53, nuclear factor-κB (NF-κB) and c-Fos.

물리적 형태

Supplied at a concentration of 1.0 mg/ml in 20 mM Tris-HCl, pH 7.5, containing 0.5 mM DTT.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable