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Merck
모든 사진(1)

문서

SRP3194

Sigma-Aldrich

CTACK (CCL27) from mouse

recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture

동의어(들):

ALP, CCL27, Cuteaneous T-cell Attracting Chemokine, Skinkine

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About This Item

UNSPSC 코드:
12352200

생물학적 소스

mouse

재조합

expressed in E. coli

분석

≥98% (HPLC)
≥98% (SDS-PAGE)

형태

lyophilized

효능

10.0-100.0 ng/mL

분자량

10.9 kDa

포장

pkg of 20 μg

기술

cell culture | mammalian: suitable

불순물

<0.1 EU/μg endotoxin, tested

색상

off-white to yellow

UniProt 수납 번호

배송 상태

wet ice

저장 온도

−20°C

유전자 정보

mouse ... CCL27(20301)

일반 설명

CTACK is a keratinocyte-derived CC chemokine which signals through the CCR10 receptor. Both CTACK and CCR10 are expressed in normal and irritated epithelial cells. CTACK selectively attracts CLA+ T-cells and directs them into the skin. CTACK contains the four highly conserved cysteine residues present in most CC chemokines. The mature protein contains 88 amino acid residues. Recombinant murine CTACK is a 10.9 kDa protein containing 95 amino acid residues.

생화학적/생리학적 작용

CTACK is a keratinocyte-derived CC chemokine which signals through the CCR10 receptor. Recombinant murine CTACK is a 10.9 kDa protein containing 95 amino acid residues.

서열

LPLPSSTSCC TQLYRQPLPS RLLRRIVHME LQEADGDCHL QAVVLHLARR SVCVHPQNRS LARWLERQGK RLQGTVPSLN LVLQKKMYSN PQQQN

물리적 형태

Lyophilized with no additives.

재구성

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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문서 라이브러리 방문

J Morales et al.
Proceedings of the National Academy of Sciences of the United States of America, 96(25), 14470-14475 (1999-12-10)
In contrast to naive lymphocytes, memory/effector lymphocytes can access nonlymphoid effector sites and display restricted, often tissue-selective, migration behavior. The cutaneous lymphocyte-associated antigen (CLA) defines a subset of circulating memory T cells that selectively localize in cutaneous sites mediated in

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