SRP0726

STK21 (CIT), Active

recombinant

• UNSPSC 코드: 12352202
• NACRES: NA.77

속성

• 재조합: expressed in baculovirus infected Sf9 cells
• 분석: 70-95% (SDS-PAGE)
• 형태: frozen liquid
• 특이 활성도: 4.0-6.0 nmol/min·mg (radiometric)
• 분자량: ~74 kDa
• 농도: 0.1 μg/μL
• 수납 번호(accession number): NM_007174
• 배송 상태: dry ice
• 저장 온도: −70°C
• 유전자 정보: human ... STK21(11113)

설명

애플리케이션

Useful for kinase assay and Western blot.

생화학적/생리학적 작용

Recombinant human STK21 (CIT) (1-449) was expressed by Baculovirus in Sf9 insect cells using an N-terminal GST tag. STK21 is a serine/threonine-protein kinase that functions in cell division and also to promote efficient cytokinesis. STK21 is a novel molecular mechanism for a subset of human malformation syndromes of the central nervous system ⁽¹⁾. STK21 is also associated with bipolar disorder and risk for schizophrenia. STK21 is a novel partner for the GTP-bound forms of rho and rac ⁽²⁾.

재구성

Formulated in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, with 25% glycerol.

저장 및 안정성

Store in aliquots at -70°C. Avoid freeze/thaw cycles.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable