생물학적 소스
mouse
재조합
expressed in baculovirus infected Sf9 cells
분석
≥65% (SDS-PAGE)
형태
aqueous solution
분자량
65 kDa
포장
pkg of 10 μg
NCBI 수납 번호
UniProt 수납 번호
배송 상태
dry ice
저장 온도
−70°C
유전자 정보
mouse ... PDE7B(29863)
일반 설명
Mouse PDE7B (GenBank Accession No. NM_013875) amino acids 108-446 (end) with N-terminal GST-tag, MW=65 kDa, expressed in a Baculovirus-infected Sf9 cell expression system.
애플리케이션
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
단위 정의
1 unit is defined as the amount of enzyme that will convert 1 pmole of 3?, 5?-cAMP to 5? AMP per min at 30°C.
Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 1
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Neuroscience, 132(4), 1173-1185 (2005-04-29)
cAMP plays an important role as second messenger molecule controlling multiple cellular processes in the brain. cAMP levels depend critically on the phosphodiesterases (PDE) activity, enzymes responsible for the clearance of intracellular cAMP. We have examined the regional distribution and
Proceedings of the National Academy of Sciences of the United States of America, 105(49), 19532-19537 (2008-11-27)
Cyclic nucleotide phosphodiesterase (PDE) isoforms can influence disease pathogenesis and be novel therapeutic targets. Because lower cAMP levels may contribute to the decreased apoptosis that occurs in chronic lymphocytic leukemia (CLL), we assessed the expression levels of PDE isoforms in
Biochemical and biophysical research communications, 272(1), 186-192 (2000-06-29)
We have identified and characterised a novel member of the PDE7 family of cyclic nucleotide phosphodiesterases (PDE), which we have designated PDE7B. Mouse and human full-length cDNAs were isolated encoding a protein of 446 and 450 amino acids, respectively. The
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