Product SRE0011 is suitable for the manufacturing of diagnostic reagents and kits. It must be stored at -20°C to maintain the 1-year warranty. Storage at 2-8°C is outside the recommended range, and the effect of prolonged storage at 2-8°C on the product's stability is unknown.
SRE0011
γ-Globulins from bovine blood
Suitable for manufacturing of diagnostic kits and reagents, ≥99% (agarose gel electrophoresis)
동의어(들):
Bovine γ-Globulin
로그인조직 및 계약 가격 보기
크기 선택
1 G
₩108,605
5 G
₩291,610
10 G
₩543,634
25 G
₩900,813
100 G
₩2,718,069
모든 사진(5)
크기 선택
보기 변경
1 G
₩108,605
5 G
₩291,610
10 G
₩543,634
25 G
₩900,813
100 G
₩2,718,069
About This Item
추천 제품
일반 설명
γ-Globulins are immunoglobulins that contain IgM, IgA, and IgY.[1] They are glycoproteins produced by plasma cells.[2] The immunoglobulins are heterodimeric molecules comprising two light chains and two heavy chains linked together by disulfide bonds.[3]
Bovine gamma globulin (BGG) is an important component of the immune system of cows and other bovines. BGG is found in the blood of bovines and is primarily used in the production of medical products such as vaccines, serums, and diagnostic reagents. BGG can also be used to treat certain medical conditions, such as hepatitis B, as well as to boost immunity in humans and other animals.
Plasma protein fraction rich in antibodies
애플리케이션
γ-Globulins from bovine blood has been used along with polyethylene glycol (PEG) to investigate the kinetics of liquid-liquid phase separation (LLPS) in its temporary and arrested state.[4] It has also been used as a parent solution to prevent bacterial growth and study the antibody system with LLPS and highly elevated protein concentrations in arrested transition.[5]
Bovine γ-globulin has been used as an immunological challenge in studies of mechanisms of immunotolerance.
생화학적/생리학적 작용
Immunoglobulins are implicated in the activation of the complement system and the opsonization of microbes for phagocytosis. It is also involved in the neutralization of toxins and viruses and blocks the attachment of microbes to mucosal surfaces. They protect our bodies against fungi, viruses, and bacteria. Immunodeficiency is associated with recurrent infectious diseases.[2]
제조 메모
Prepared from Cohn Fraction II, III
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
시험 성적서(COA)
Lot/Batch Number
이미 열람한 고객
Blood
Sturkie's Avian Physiology, 167-191, 167-191 (2015)
Stefano Da Vela et al.
Soft matter, 13(46), 8756-8765 (2017-11-14)
We investigate the transition of the phase separation kinetics from a complete to an arrested liquid-liquid phase separation (LLPS) in mixtures of bovine γ-globulin with polyethylene glycol (PEG). The solutions feature LLPS with upper critical solution temperature phase behavior. At
Anita Girelli et al.
Molecular pharmaceutics, 18(11), 4162-4169 (2021-10-13)
Antibody therapies are typically based on high-concentration formulations that need to be administered subcutaneously. These conditions induce several challenges, inter alia a viscosity suitable for injection, sufficient solution stability, and preservation of molecular function. To obtain systematic insights into the
Justiz Vaillant AA, et al.
Immunoglobulin (2021)
Harry W Schroeder et al.
The Journal of allergy and clinical immunology, 125(2 Suppl 2), S41-S52 (2010-03-05)
Immunoglobulins are heterodimeric proteins composed of 2 heavy and 2 light chains. They can be separated functionally into variable domains that bind antigens and constant domains that specify effector functions, such as activation of complement or binding to Fc receptors.
-
Can Gamma-Globulins be stored at 2 - 8 C without affecting shelf life, considering the Certificate of Analysis specifies a storage temperature of -20 C?
1 답변-
도움이 되었습니까?
-
-
Dear sir or madam, Can you please let me know what is the shelf life for this reference
1 답변-
This product is not assigned an expiration date. It is assigned a recommended retest date of 2 years after the quality release date. A recommended retest date is the time during which the product is expected to remain within established stability specifications, provided that it has been stored under defined conditions. After the Retest Date, product samples should be examined to ensure that the product is still in compliance with the established specifications.
For more information, you may access the "Product Dating Information" document under "ADDITIONAL USEFUL DOCUMENTS ABOUT OUR PRODUCTS" at the bottom of the Quality Services page with this link: https://www.sigmaaldrich.com/US/en/life-science/quality-and-regulatory-management/quality-services.
도움이 되었습니까?
-
활성 필터
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.
