SML3158

6-Methylflavone

≥98% (HPLC)

• 동의어(들): 6-Methyl-2-phenyl-4H-1-benzopyran-4-one, 6-Methyl-2-phenyl-4H-chromen-4-one
• 실험식(Hill 표기법): C₁₆H₁₂O₂
• CAS Number: 29976-75-8
• Molecular Weight: 236.27
• MDL number: MFCD00017461
• UNSPSC 코드: 51111800
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 형태: powder
• 색상: white to beige
• mp: 119-122 °C (dec.) (lit.)
• solubility: DMSO: 2 mg/mL, clear (warmed)
• 저장 온도: 2-8°C
• SMILES string: Cc1ccc2OC(=CC(=O)c2c1)c3ccccc3
• InChI: 1S/C16H12O2/c1-11-7-8-15-13(9-11)14(17)10-16(18-15)12-5-3-2-4-6-12/h2-10H,1H3
• InChI key: NOQJBXPAMJLUSS-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

6-Methylflavone is a bitter taste blocker that significantly reduces bitter test of HIV drug tenofovir alafenamide in human subjects. 6-Methylflavone is a selective and potent modulator of TAS2R39 bitter test receptor that blocks it response to tenofovir alafenamide. 6-Methylflavone is a positive allosteric modulator (PAM) of α1β2γ2L and α1β2 GABAA receptors.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable