추천 제품
Quality Level
분석
≥98% (HPLC)
형태
powder
저장 조건
desiccated
색상
white to beige
solubility
H2O: 20 mg/mL, clear
저장 온도
−20°C
SMILES string
OB(O)CCSC[C@H](N)C(O)=O.C
InChI
1S/C5H12BNO4S.CH4/c7-4(5(8)9)3-12-2-1-6(10)11;/h4,10-11H,1-3,7H2,(H,8,9);1H4/t4-;/m0./s1
InChI key
IMYJQAMXIIYUIH-WCCKRBBISA-N
생화학적/생리학적 작용
BEC (S-(2-boronoethyl)-l-cysteine) is a potent and specific arginase inhibitor that restores flow-induced responses in arterioles from diabetic rats.
BEC is a boronic analog of L-arginine, and L-cysteine. It competitively inhibits both arginase I and II. BEC does not directly affect nitric oxide synthase.
신호어
Warning
유해 및 위험 성명서
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
표적 기관
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Arginase inhibition restores arteriolar endothelial function in Dahl rats with salt-induced hypertension
Johnson FK, et al.
American Journal of Physiology. Lung Cellular and Molecular Physiology, 288(4), R1057-R1062 (2005)
Amino Acids in Human Nutrition and Health, 62-62 (2012)
Alessandra Romano et al.
Expert review of molecular diagnostics, 18(7), 675-683 (2018-05-01)
Despite improvement in overall response due to the introduction of the first-in-class proteasome inhibitor bortezomib (btz), multiple myeloma (MM) is still an incurable disease due to the immune-suppressive bone marrow (BM) environment. Thus, the authors aimed to identify the role
Barbara Érsek et al.
Cellular and molecular life sciences : CMLS, 78(2), 661-673 (2020-04-25)
This study shows that melanoma-associated fibroblasts (MAFs) suppress cytotoxic T lymphocyte (CTL) activity and reveals a pivotal role played by arginase in this phenomenon. MAFs and normal dermal fibroblasts (DFs) were isolated from surgically resected melanomas and identified as Melan-A-/gp100-/FAP+ cells.
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