SML0953

Cirsiliol

≥90% (HPLC)

• 동의어(들): 2-(3,4-Dihydroxyphenyl)-5-hydroxy-6,7-dimethoxy-4H-1-benzopyran-4-one, 3′,4′,5-Trihydroxy-6,7-dimethoxy-flavone, 5,3′,4′-Trihydroxy-6,7-dimethoxyflavone, 6,7-Dimethoxy-5,3′,4′-trihydroxyflavone, 6-Hydroxyluteolin-6,7-dimethyl ether, 6-Methoxyluteolin 7-methyl ether, Crisiliol
• 실험식(Hill 표기법): C₁₇H₁₄O₇
• CAS Number: 34334-69-5
• Molecular Weight: 330.29
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• 분석: ≥90% (HPLC)
• 형태: powder
• 저장 조건: protect from light
• 색상: white to beige
• solubility: DMSO: 10 mg/mL, clear
• 저장 온도: 2-8°C
• InChI: 1S/C17H14O7/c1-22-14-7-13-15(16(21)17(14)23-2)11(20)6-12(24-13)8-3-4-9(18)10(19)5-8/h3-7,18-19,21H,1-2H3
• InChI key: IMEYGBIXGJLUIS-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

Cirsiliol is a flavonoid that displays anti-inflammatory, anti-oxidant, anti-proliferative, and anti-bacterial activities. Cirsiliol sensitizes non-small cell lung cancer cell lines (NSCLC) to radiation therapy. Cirsiliol inhibits epithelial-mesenchymal transition likely by induction of tumor-suppressive miR-34a, which suppresses Notch-1 expression NSCLC.

특징 및 장점

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안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302
• 예방조치 성명서: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable