SML0803

VUF10661

≥98% (HPLC), Chemokine receptor CXCR3 agonist, powder

• 동의어(들): (3S)-N-[(1S)-5-Amino-1-[[(2,2-diphenylethyl)amino]carbonyl]pentyl]-2-(1,4-dioxo-4-phenylbutyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide
• 실험식(Hill 표기법): C₄₀H₄₄N₄O₄
• CAS 번호: 914291-63-7
• Molecular Weight: 644.80
• UNSPSC Code: 51111800
• NACRES: NA.77
• Assay: ≥98% (HPLC)
• Form: powder

속성

• 제품 이름: VUF10661, ≥98% (HPLC)
• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 10 mg/mL, clear
• storage temp.: −20°C

설명

Biochem/physiol Actions

VUF10661 is a potent agonist of the chemokine receptor CXCR3.

VUF10661 is a potent agonist of the chemokine receptor CXCR3. VUF10661 induces receptor internalization, recruitment of ?-arrestins and activates Gi proteins with similar potency to endogenous CXCL ligands.

Features and Benefits

This compound is featured on the Chemokine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

안전성 정보

• 픽토그램: GHS06
• 경고어: Danger
• 위험 코드: H301,H315,H319,H335,H413
• 주의 사항: P273 - P301 + P310 + P330 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Oral - Aquatic Chronic 4 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 표적 장기: Respiratory system
• 저장 등급: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• 무슨 일이 일어나고 있는 걸까?: WGK 3
• 인화점 (F): Not applicable
• 인화점 (°C): Not applicable