SML0334

DMPQ dihydrochloride

≥98% (HPLC)

• 동의어(들): 5,7-Dimethoxy-3-(4-pyridinyl)quinoline dihydrochloride
• 실험식(Hill 표기법): C₁₆H₁₄N₂O₂ · 2HCl
• CAS Number: 1123491-15-5
• Molecular Weight: 339.22
• MDL number: MFCD02262123
• UNSPSC 코드: 12352200
• PubChem Substance ID: 329825339
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 형태: powder
• 저장 조건: desiccated
• 색상: white to beige
• solubility: H₂O: >10 mg/mL
• 저장 온도: room temp
• SMILES string: Cl.Cl.COc1cc(OC)c2cc(cnc2c1)-c3ccncc3
• InChI: 1S/C16H14N2O2.2ClH/c1-19-13-8-15-14(16(9-13)20-2)7-12(10-18-15)11-3-5-17-6-4-11;;/h3-10H,1-2H3;2*1H
• InChI key: YBBAOKYVJCNJIV-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

DMPQ is a potent selective inhibitor of human vascular beta-type platelet derived growth factor receptor tyrosine kinase (PDGFR?) with IC₅₀ = 80 nM. It is > 100-fold selective over EGFR, erbB2, p56, protein kinase A and protein kinase C.

특징 및 장점

This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the PDGFR page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302
• 예방조치 성명서: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable