크기 선택
1 MG
₩306,632
5 MG
₩1,146,138
모든 사진(1)
크기 선택
보기 변경
1 MG
₩306,632
5 MG
₩1,146,138
About This Item
실험식(Hill 표기법):
C32H44N6O7
Molecular Weight:
624.73
UNSPSC 코드:
12352200
NACRES:
NA.32
추천 제품
분석
≥95% (HPLC)
양식
lyophilized
구성
Peptide Content, ≥85%
저장 조건
protect from light
저장 온도
−20°C
Amino Acid Sequence
Asp-Pro-Ile-Leu-Trp
애플리케이션
JKC-301 (Asp-Pro-Ile-Leu-Trp) is a pentapeptide used as an selective endothelin ET(A) receptor antagonist.
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
J E Tanus-Santos et al.
European journal of pharmacology, 396(1), 33-37 (2000-05-24)
The increased endothelin-1 levels observed after smoking may result from nicotine-stimulated endothelin-1 production by endothelial cells. In this study, we investigated the effects of selective endothelin ET(A) receptors antagonist Cycle D-a-aspartyl-L-prolyl-D-isoleucyl-D-tryptophyl (JKC 301) and of endothelin ET(B) receptors antagonist N-cis-2
Z Fekete et al.
The Journal of pharmacology and experimental therapeutics, 275(1), 215-218 (1995-10-01)
In this study we characterized the endothelin (ET) receptors of cultured L6 myotubes in order to gain a further insight into the mechanism of the ET effect on skeletal muscle cells. Displacements of 125I-ET-1 by unlabeled ET-1, ET-2 and ET-3
L C Ngoka et al.
Journal of mass spectrometry : JMS, 35(2), 265-276 (2000-02-19)
We previously showed by using mass spectrometry that endothelin A selective receptor antagonists BQ123 and JKC301 form novel coordination compounds with sodium ions. This property may underlie the ability of an ET(A) antagonist to induce net tubular sodium reabsorption in
Daphne Merkus et al.
American journal of physiology. Heart and circulatory physiology, 288(5), H2088-H2092 (2005-01-08)
Alpha-adrenergic vasoconstriction in the coronary circulation is mediated through alpha-adrenoceptors on cardiac myocytes and subsequent release of endothelin, a very potent, long-lasting vasoconstrictor. Recent studies found that adult cardiac myocytes do not express the preproendothelin gene. Thus we hypothesized that
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