SBR00088

Rilpivirine

≥95% (HPLC), powder

• 동의어(들): 4-[[4-[[4-[(1E)-2-Cyanoethenyl]-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino]benzonitrile, R 278474, TMC 278
• 실험식(Hill 표기법): C₂₂H₁₈N₆
• CAS Number: 500287-72-9
• Molecular Weight: 366.42
• MDL number: MFCD11046372
• UNSPSC 코드: 51101500

속성

• Quality Level: 100
• 분석: ≥95% (HPLC)
• 형태: powder
• 색상: white to yellow, or beige
• 항생제 활성 스펙트럼: viruses
• 동작 모드: enzyme | inhibits
• 배송 상태: ambient
• 저장 온도: −20°C
• SMILES string: CC1=CC(=CC(=C1NC2=NC(=NC=C2)NC3=CC=C(C=C3)C#N)C)/C=C/C#N
• InChI: 1S/C22H18N6/c1-15-12-18(4-3-10-23)13-16(2)21(15)27-20-9-11-25-22(28-20)26-19-7-5-17(14-24)6-8-19/h3-9,11-13H,1-2H3,(H2,25,26,27,28)/b4-3+
• InChI key: YIBOMRUWOWDFLG-ONEGZZNKSA-N

설명

일반 설명

Rilpivirine is an antibiotic which belongs to the class of compounds known as non-nucleoside reverse transcriptase inhibitors (NNRTIs).

생화학적/생리학적 작용

Rilpivirine inhibits the activity of the reverse transcriptase enzyme, which is essential for the replication of HIV-1. Specifically, it binds to a specific site on the enzyme and blocks its activity, thereby preventing the conversion of viral RNA into DNA, which is an essential step for the integration of viral DNA into host cells.

Rilpivirine is a next generation nonnucleoside reverse transcriptase inhibitor (NNRTI), It has been shown to be active against many HIV strains with mutations that confer resistance to the first-generation NNRTIs.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable