추천 제품
재조합
expressed in human cells
형태
liquid
배송 상태
dry ice
저장 온도
−70°C
일반 설명
SOLVO Biotechnology offers ready-to-use assay kits for efflux and uptake transporters. SOLVO′s PREDIVEZ Vesicular Transport Assay Kits are suitable for efflux transporter inhibition studies. The kits are designed to test the inhibitory effect of one or more test compounds on the vesicular transport of a probe substrate. In most cases a fluorescent probe substrate is included. Kits contain all reagents and solutions necessary to conduct the drug-transporter interaction assay of need.
애플리케이션
PREDIVEZ™ vesicular transport reagent Kit may be used for assessing human ATP binding cassette subfamily B member 1 (ABCB1) function and multidrug resistance-associated protein 2 (MRP2) efflux transporter function.
The PREDIVEZ Vesicular Transport Kit is a simple and powerful tool to investigate drug transporter interactions. It provides information on any interaction between the ABC transporter and the drug candidate that would affect the transport of the fluorescent or radiolabeled or cold.
PREDIVEZ vesicular transport kits contains buffers, probe substrate, and reference inhibitors needed to run vesicular transport assays (sufficient for 300 wells/kit –equivalent to existing 9-cpd PV kits). Assay protocol, calculation template, and example data file available on SOLVO website.
Transport membranes and control membranes are sold separately. This PREDIVEZ vesicular transport kit requires the transporter membranes and corresponding control membrane below:
SSB-BCRP-M-VT BCRP human membrane vesicles part number SBVT09-1EA and corresponding control membrane SB-M-CTRL part number SBCT02-1EA
SB-BCRP-HEK293-VT BCRP human membrane vesicles part number SBVT17-1EA and corresponding control membrane SB-HEK293-Mock-CTRL part number SBCT06-1EA
PREDIVEZ vesicular transport kits contains buffers, probe substrate, and reference inhibitors needed to run vesicular transport assays (sufficient for 300 wells/kit –equivalent to existing 9-cpd PV kits). Assay protocol, calculation template, and example data file available on SOLVO website.
Transport membranes and control membranes are sold separately. This PREDIVEZ vesicular transport kit requires the transporter membranes and corresponding control membrane below:
SSB-BCRP-M-VT BCRP human membrane vesicles part number SBVT09-1EA and corresponding control membrane SB-M-CTRL part number SBCT02-1EA
SB-BCRP-HEK293-VT BCRP human membrane vesicles part number SBVT17-1EA and corresponding control membrane SB-HEK293-Mock-CTRL part number SBCT06-1EA
법적 정보
PREDIVEZ is a trademark of Solvo Biotechnology
신호어
Warning
유해 및 위험 성명서
Hazard Classifications
Met. Corr. 1 - Skin Sens. 1
Storage Class Code
8A - Combustible corrosive hazardous materials
Flash Point (°F)
188.6 °F
Flash Point (°C)
87 °C
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Impact of probe compound in MRP2 vesicular transport assays
European Journal of Pharmaceutical Sciences, 46(1-2), 100-105 (2012)
ABCB1 transports Seliciclib (R-Roscovitine), a cyclin-dependent kinase inhibitor
Drug Metabolism and Disposition, dmd-110 (2010)
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