추천 제품
생물학적 소스
rabbit
Quality Level
material
colorless
클론
5O7P1, monoclonal
양식
liquid
분자량
26 kDa
종 반응성
human
농도
2 mg/mL
기술
western blot: 1:500 - 1:2000
색상
colorless
동형
IgG
면역원 서열
MAPFEPLASGILLLLWLIAPSRACTCVPPHPQTAFCNSDLVIRAKFVGTPEVNQTTLYQRYEIKMTKMYKGFQALGDAADIRFVYTPAMESVCGYFHRSH
UniProt 수납 번호
배송 상태
wet ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... TIMP1(7076)
일반 설명
This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. [provided by RefSeq, Jul 2008]
면역원
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human TIMP1 (P01033).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
애플리케이션
WB
Storage Class Code
10 - Combustible liquids
WGK
WGK 1
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