생물학적 소스
rabbit
Quality Level
material
colorless
클론
2S1I10, monoclonal
양식
liquid
분자량
26 kDa
종 반응성
human, rat, rat
농도
0.70 mg/mL
기술
immunofluorescence: 1:50 - 1:200
western blot: 1:10000 - 1:20000
색상
colorless
동형
IgG
면역원 서열
MGSVSNQQFAGGCAKAAEEAPEEAPEDAARAADEPQLLHGAGICKWFNVRMGFGFLSMTARAGVALDPPVDVFVHQSKLHMEGFRSLKEGEAVEFTFKKS
UniProt 수납 번호
배송 상태
wet ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... LIN28A(79727)
일반 설명
This gene encodes a LIN-28 family RNA-binding protein that acts as a posttranscriptional regulator of genes involved in developmental timing and self-renewal in embryonic stem cells. The encoded protein functions through direct interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development. This protein prevents the terminal processing of the LET7 family of microRNAs which are major regulators of cellular growth and differentiation. Aberrant expression of this gene is associated with cancer progression in multiple tissues. [provided by RefSeq, Sep 2015]
면역원
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human LIN28A (Q9H9Z2).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
애플리케이션
WB, IF/ICC
Storage Class Code
10 - Combustible liquids
WGK
WGK 1
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