SAB5702738

Anti-LIN28A Antibody, clone 2S1I10, Rabbit Monoclonal

• 동의어(들): CSDD1, LIN-28, LIN28, ZCCHC1, lin-28A
• UNSPSC 코드: 12352203
• NACRES: NA.46

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• material: colorless
• 클론: 2S1I10, monoclonal
• 양식: liquid
• 분자량: 26 kDa
• 종 반응성: human, rat, rat
• 농도: 0.70 mg/mL
• 기술: immunofluorescence: 1:50 - 1:200; western blot: 1:10000 - 1:20000
• 색상: colorless
• 동형: IgG
• 면역원 서열: MGSVSNQQFAGGCAKAAEEAPEEAPEDAARAADEPQLLHGAGICKWFNVRMGFGFLSMTARAGVALDPPVDVFVHQSKLHMEGFRSLKEGEAVEFTFKKS
• UniProt 수납 번호: Q9H9Z2
• 배송 상태: wet ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... LIN28A(79727)

설명

일반 설명

This gene encodes a LIN-28 family RNA-binding protein that acts as a posttranscriptional regulator of genes involved in developmental timing and self-renewal in embryonic stem cells. The encoded protein functions through direct interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development. This protein prevents the terminal processing of the LET7 family of microRNAs which are major regulators of cellular growth and differentiation. Aberrant expression of this gene is associated with cancer progression in multiple tissues. [provided by RefSeq, Sep 2015]

면역원

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human LIN28A (Q9H9Z2).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

애플리케이션

WB, IF/ICC

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1