SAB5702162

Anti-Serotonin transporter Antibody, clone 5T7M2, Rabbit Monoclonal

• 동의어(들): 5-HTT,5-HTTLPR,5HTT,HTT,OCD1,SERT,SERT1,hSERT,SLC6A4
• UNSPSC 코드: 12352203
• NACRES: NA.46

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• material: colorless
• 클론: 5T7M2, monoclonal
• 양식: liquid
• 분자량: 70 kDa
• 종 반응성: human, rat
• 농도: 0.25 mg/mL
• 기술: immunofluorescence: 1:50 - 1:200; western blot: 1:500 - 1:1000
• 색상: colorless
• 동형: IgG
• 면역원 서열: METTPLNSQKQLSACEDGEDCQENGVLQKVVPTPGDKVESGQISNGYSAVPSPGAGDDTRHSIPATTTTLVAELHQGERETWGKKVDFLLSVIGYAVDLG
• UniProt 수납 번호: P31645
• 배송 상태: wet ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... SLC6A4(6532)

설명

일반 설명

This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma. [provided by RefSeq, Jul 2008]

면역원

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Serotonin transporter (P31645).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

애플리케이션

WB, IF/ICC

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1