SAB5701912

Anti-Phospho-PKC zeta-T560 antibody produced in rabbit

• UNSPSC 코드: 12352203
• NACRES: NA.43

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 항체 생산 유형: primary antibodies
• 클론: monoclonal
• 양식: liquid
• 종 반응성: human
• 농도: 1.05 mg/mL
• 기술: western blot: 1:500-1:2000
• UniProt 수납 번호: Q05513
• 배송 상태: wet ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: phosphorylation (pThr560)
• 유전자 정보: human ... PRKCZ(5590)

설명

일반 설명

Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

면역원

A phospho specific peptide corresponding to residues surrounding T560 of human PKC zeta

물리적 형태

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable