SAB5700412

Anti-Phospho-RB1-S608 antibody produced in rabbit

• 동의어(들): OSRC, PPP1R130, RB, RB1, Rb, p105-Rb, pRb, pp110
• UNSPSC 코드: 12352203
• NACRES: NA.43

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 형태: buffered aqueous solution
• 분자량: 106
• 종 반응성: human
• 농도: 6.29 mg/ml
• 기술: western blot: 1:500-1:2000
• UniProt 수납 번호: P06400
• 배송 상태: wet ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: phosphorylation (pSer608)
• 유전자 정보: human ... RB1(5925)

설명

일반 설명

The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

면역원

A synthetic phosphorylated peptide around S608 of human RB1 (NP_000312.2).

물리적 형태

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

저장 및 안정성

Store at -20℃. Avoid freeze / thaw cycles.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable