SAB4702104

Monoclonal Anti-CD271, purified produced in mouse

• 동의어(들): NGFR, TNFRSF16, p75NGFR, p75NTR
• UNSPSC 코드: 12352203

속성

• 결합: unconjugated
• Quality Level: 100
• 항체 생산 유형: primary antibodies
• 클론: NGFR5, monoclonal
• 형태: buffered aqueous solution
• 종 반응성: human, ( Non-human primates), ( Rabbit), ( Cat)
• 농도: 1 mg/ml
• 기술: flow cytometry: suitable; immunocytochemistry: suitable; immunohistochemistry: suitable; immunoprecipitation (IP): suitable; western blot: suitable
• 동형: IgG1
• UniProt 수납 번호: P08138
• 저장 온도: 2-8°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... NGFR(4804)

설명

일반 설명

CD271 / NGFR, also known as p75NGFR or p75NTR, is a 75 kDa low affinity receptor for the NGF (nerve growth factor), BDNF (brain-derived growth factor), and other neurotrophins, such as NT3 and NT4/5. Unlike other members of the tumor necrosis factor receptor superfamily of transmembrane proteins, CD271 has unique intracellular domain structure (lacks catalytic activity) and downstream signaling partners. Triggered by its ligands CD271 affects growth, differentiation, migration and death of the nervous system cells.

특이성

The mouse monoclonal antibody NGFR5 (originally C34C) recognizes an epitope within ammino acids 1 - 160 of CD271/NGFR, a 75 kDa transmembrane glycoprotein of the TNFR superfamily.

면역원

Purified CD271 protein isolated from human melanoma cell line A875

물리적 형태

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

제조 메모

Purified by protein-A affinity chromatography.

저장 및 안정성

Store at 2-8°C. Do not freeze.

기타 정보

The antibody solution should be gently mixed before use.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable