추천 제품
생물학적 소스
rabbit
결합
unconjugated
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
polyclonal
형태
buffered aqueous solution
분자량
antigen 51 kDa
종 반응성
rat, human, mouse
농도
~1 mg/mL
기술
ELISA: 1:10000
western blot: 1:500-1:1000
NCBI 수납 번호
UniProt 수납 번호
배송 상태
wet ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... RXFP3(51289)
일반 설명
Anti-RXFP3 Antibody detects endogenous levels of total RXFP3 protein.
RXFP3 (relaxin family peptide receptor 3) is also termed as GPCR 135/ SALPR (somatostatin- and angiotensin- like peptide receptor). It is distributed in the central nervous system (CNS), mainly in areas associated with memory, sensory and emotional processing. RXFP3 belongs to the insulin superfamily. This gene is mapped to human chromosome 5p13.
RXFP3 (relaxin family peptide receptor 3) is also termed as GPCR 135/ SALPR (somatostatin- and angiotensin- like peptide receptor). It is distributed in the central nervous system (CNS), mainly in areas associated with memory, sensory and emotional processing. RXFP3 belongs to the insulin superfamily. This gene is mapped to human chromosome 5p13.
면역원
The antiserum was produced against synthesized peptide derived from human RXFP3.
Immunogen Range: 161-210
Immunogen Range: 161-210
생화학적/생리학적 작용
RXFP3 (relaxin family peptide receptor 3) acts as the cognate receptor for relaxin-3. It controls feeding, motivated behaviors, stress and anxiety. RXFP3 system also modulates alcohol-seeking.
특징 및 장점
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물리적 형태
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage Class Code
10 - Combustible liquids
WGK
nwg
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
In vitro pharmacological characterization of RXFP3 allosterism: an example of probe dependency.
PLoS ONE, 7(2), e30792-e30792 (2012)
Hydrocarbon stapled B chain analogues of relaxin-3 retain biological activity.
Peptides, 84, 44-57 (2016)
5p13. 3p13. 2 duplication associated with developmental delay, congenital malformations and chromosome instability manifested as low-level aneuploidy.
SpringerPlus, 4(1), 616-616 (2015)
Role of relaxin-3/RXFP3 system in stress-induced binge-like eating in female rats.
Neuropharmacology, 102, 207-215 (2016)
Proceedings of the National Academy of Sciences of the United States of America, 110(51), 20789-20794 (2013-12-04)
Relapse and hazardous drinking represent the most difficult clinical problems in treating patients with alcohol use disorders. Using a rat model of alcohol use and alcohol-seeking, we demonstrated that central administration of peptide antagonists for relaxin family peptide 3 receptor
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