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Merck
모든 사진(1)

문서

SAB4502117

Sigma-Aldrich

Anti-RXFP3 antibody produced in rabbit

affinity isolated antibody

동의어(들):

G protein-coupled receptor SALPR, GPCR135, RLN3 receptor 1, Relaxin family peptide receptor 3, Somatostatin- and angiotensin-like peptide receptor

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About This Item

UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

rabbit

결합

unconjugated

항체 형태

affinity isolated antibody

항체 생산 유형

primary antibodies

클론

polyclonal

형태

buffered aqueous solution

분자량

antigen 51 kDa

종 반응성

rat, human, mouse

농도

~1 mg/mL

기술

ELISA: 1:10000
western blot: 1:500-1:1000

NCBI 수납 번호

UniProt 수납 번호

배송 상태

wet ice

저장 온도

−20°C

타겟 번역 후 변형

unmodified

유전자 정보

human ... RXFP3(51289)

일반 설명

Anti-RXFP3 Antibody detects endogenous levels of total RXFP3 protein.
RXFP3 (relaxin family peptide receptor 3) is also termed as GPCR 135/ SALPR (somatostatin- and angiotensin- like peptide receptor). It is distributed in the central nervous system (CNS), mainly in areas associated with memory, sensory and emotional processing. RXFP3 belongs to the insulin superfamily. This gene is mapped to human chromosome 5p13.

면역원

The antiserum was produced against synthesized peptide derived from human RXFP3.

Immunogen Range: 161-210

생화학적/생리학적 작용

RXFP3 (relaxin family peptide receptor 3) acts as the cognate receptor for relaxin-3. It controls feeding, motivated behaviors, stress and anxiety. RXFP3 system also modulates alcohol-seeking.

특징 및 장점

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

물리적 형태

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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Storage Class Code

10 - Combustible liquids

WGK

nwg

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리 방문

In vitro pharmacological characterization of RXFP3 allosterism: an example of probe dependency.
Alvarez-Jaimes L, et al.
PLoS ONE, 7(2), e30792-e30792 (2012)
Hydrocarbon stapled B chain analogues of relaxin-3 retain biological activity.
Jayakody T, et al.
Peptides, 84, 44-57 (2016)
5p13. 3p13. 2 duplication associated with developmental delay, congenital malformations and chromosome instability manifested as low-level aneuploidy.
Iourov IY, et al.
SpringerPlus, 4(1), 616-616 (2015)
Role of relaxin-3/RXFP3 system in stress-induced binge-like eating in female rats.
Calvez J, et al.
Neuropharmacology, 102, 207-215 (2016)
Philip J Ryan et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(51), 20789-20794 (2013-12-04)
Relapse and hazardous drinking represent the most difficult clinical problems in treating patients with alcohol use disorders. Using a rat model of alcohol use and alcohol-seeking, we demonstrated that central administration of peptide antagonists for relaxin family peptide 3 receptor

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