추천 제품
생물학적 소스
rabbit
결합
unconjugated
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
polyclonal
형태
buffered aqueous solution
분자량
antigen 35 kDa
종 반응성
human
농도
~1 mg/mL
기술
ELISA: 1:40000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI 수납 번호
UniProt 수납 번호
배송 상태
wet ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... MT-ND1(4535)
일반 설명
Anti-MT-ND1 Antibody detects endogenous levels of total MT-ND1 protein.
MT-ND1 (mitochondrially encoded NADH dehydrogenase 1mt-Nd1) codes for NADH dehydrogenase-1.
MT-ND1 (mitochondrially encoded NADH dehydrogenase 1mt-Nd1) codes for NADH dehydrogenase-1.
면역원
The antiserum was produced against synthesized peptide derived from human MT-ND1.
Immunogen Range: 176-225
Immunogen Range: 176-225
생화학적/생리학적 작용
MT-ND1 (mitochondrially encoded NADH dehydrogenase 1mt-Nd1) plays a vital role in the electron transport chain of oxidative phosphorylation (OXPHOS). Mutations in MT-ND1 gene is observed in individuals with LHON (leber′s hereditary optic neuropathy). Mutation in MT-ND1 results in dextrocardia, ventriculoarterial discordance and tricuspid atresia.
특징 및 장점
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
물리적 형태
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
nwg
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Genetic diversities of MT-ND1 and MT-ND2 genes are associated with high-altitude adaptation in yak.
Shi Y, et al.
Mitochondrial DNA. Part A, DNA mapping, sequencing, and analysis, 29(3), 485-494 (2018)
Determination of a New Mutation in MT?ND 1 Gene of a Patient With Dextrocardia, Ventriculoarterial Discordance, and Tricuspid Atresia.
Hatemi AC, et al.
Artificial Organs, 39(1), 83-84 (2015)
Mitochondrial ND1 variants in 1281 Chinese subjects with Leber's hereditary optic neuropathy.
Ji Y, et al.
Investigative Ophthalmology & Visual Science, 57(6), 2377-2389 (2016)
Engy A Abdel-Rahman et al.
Journal of advanced research, 31, 35-47 (2021-07-02)
Incidents of myocardial infarction and sudden cardiac arrest vary with time of the day, but the mechanism for this effect is not clear. We hypothesized that diurnal changes in the ability of cardiac mitochondria to control calcium homeostasis dictate vulnerability
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