SAB4500397

Anti-Collagen XIII α1 antibody produced in rabbit

affinity isolated antibody

• 동의어(들): CODA1, COLXIIIA1, Collagen α-1(XIII) chain
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• 결합: unconjugated
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 형태: buffered aqueous solution
• 분자량: antigen 69 kDa
• 종 반응성: human, mouse
• 농도: ~1 mg/mL
• 기술: ELISA: 1:20000; immunofluorescence: 1:100-1:500
• NCBI 수납 번호: Q5TAT6
• UniProt 수납 번호: Q5TAT6
• 배송 상태: wet ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... COL13A1(1305)

설명

일반 설명

The COL13A1 (collagen type XIII α-1 chain) gene is mapped to human chromosome 10q22.1. It codes for the α-chain of a group of non-fibrillar collagen. The protein is homotrimeric containing a single transmembrane region with intracellular and extracellular domains. The ectodomain contains three alternating collagenous and non-collagenous domains. COL13A1 is expressed in the muscle motor endplate. Anti-Collagen XIII α1 Antibody detects endogenous levels of total Collagen XIII α1 protein.

면역원

The antiserum was produced against synthesized peptide derived from human Collagen XIII alpha1.

Immunogen Range: 641-690

생화학적/생리학적 작용

Collagen XIII α1 (COL13A1) is an oncogene, promoting invasion in cancer. Upregulation of COL13A1 gene is observed in bladder cancer. COL13A1 is associated with neuromuscular junction organization. Mutation in the gene leads to myasthenic disorder.

특징 및 장점

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물리적 형태

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: nwg
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable