SAB4500130

Anti-Centromeric Protein A antibody produced in rabbit

affinity isolated antibody

• 동의어(들): CENA, CENP-A, CENPA, Centromere autoantigen A, Centromere protein A
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• 결합: unconjugated
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 형태: buffered aqueous solution
• 분자량: antigen 15 kDa
• 종 반응성: human
• 농도: ~1 mg/mL
• 기술: ELISA: 1:10000; immunofluorescence: 1:100-1:500; immunohistochemistry: 1:50-1:100
• NCBI 수납 번호: P49450
• UniProt 수납 번호: P49450
• 배송 상태: wet ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... CENPA(1058)

설명

일반 설명

Anti-Centromeric protein A Antibody detects endogenous levels of total Centromeric protein A protein.

Centromeric Protein A (CENPA), is encoded by the gene mapped to human chromosome 2p23.3. The encoded protein is a longer variant of histone H3 in humans.

면역원

The antiserum was produced against synthesized peptide derived from human Centromeric Protein A.

Immunogen Range: 1-50

생화학적/생리학적 작용

Centromeric Protein A (CENPA) plays a vital role in centromere specification and facilitates its mitotic function and epigenetic maintenance. CENP-A-nucleosome associated complex (NAC) is implicated in the regulation of chromosome congression and spindle bipolarity. Disorganization of this complex leads to change in chromosome alignment and segregation that prevent cell survival regardless of continued centromere-derived mitotic checkpoint signaling.

특징 및 장점

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

물리적 형태

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: nwg
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable