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Merck
모든 사진(2)

Key Documents

SAB4300561

Sigma-Aldrich

Anti-SMAD1 (Ab-465) antibody produced in rabbit

affinity isolated antibody

동의어(들):

Anti-BSP1 antibody produced in rabbit, Anti-JV4-1 antibody produced in rabbit, Anti-JV41 antibody produced in rabbit, Anti-MADH1 antibody produced in rabbit, Anti-SMAD family member 1 antibody produced in rabbit

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About This Item

UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

rabbit

결합

unconjugated

항체 형태

affinity isolated antibody

항체 생산 유형

primary antibodies

클론

polyclonal

형태

buffered aqueous solution

분자량

~55 kDa

종 반응성

mouse, rat, human

농도

1 mg/mL

기술

indirect immunofluorescence: 1:100-1:200
western blot: 1:500-1:1000

동형

IgG

면역원 서열

(I-S-S-V-S)

NCBI 수납 번호

UniProt 수납 번호

배송 상태

wet ice

저장 온도

−20°C

타겟 번역 후 변형

unmodified

유전자 정보

human ... SMAD1(4086)

일반 설명

Smad1 (SMAD family member 1) is a transcriptional activator, that is located on chromosome 4q31.

면역원

Peptide sequence around aa. 461-465 (I-S-S-V-S), according to the protein SMAD1.

생화학적/생리학적 작용

SMAD1 (SMAD family member 1) protein has a major role in disease development, hence it acts as a biologic prognostic factor in diseases. The miR-345 repress the multiplication, invasion and migration of prostate cancer by downregulating Smad1.

특징 및 장점

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

표적 설명

Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD).

물리적 형태

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

The distribution and potential prognostic value of SMAD protein expression in chronic lymphocytic leukemia
Witkowska M, et al.
Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine, 39(3) (2017)
An interstitial 4q31.21q31.22 microdeletion associated with developmental delay: case report and literature review
Vlaikou AM, et al.
Cytogenetic and genome research, 142(4), 227-238 (2014)
Integrating patterning signals: Wnt/GSK3 regulates the duration of the BMP/Smad1 signal
Fuentealba LC, et al.
Cell, 131(5), 980-993 (2007)
MiR-345 suppresses proliferation, migration and invasion by targeting Smad1 in human prostate cancer
Chen QG, et al.
Journal of Cancer Research and Clinical Oncology, 142(1), 213-224 (2016)

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