SAB4300427

Anti-PAK1 (Ab-212) antibody produced in rabbit

affinity isolated antibody

• 동의어(들): Anti-MGC130000 antibody produced in rabbit, Anti-MGC130001 antibody produced in rabbit, Anti-PAKalpha antibody produced in rabbit, Anti-p21 protein (Cdc42 / Rac)-activated kinase 1 antibody produced in rabbit
• MDL number: MFCD03457569
• UNSPSC 코드: 12352203

속성

• 생물학적 소스: rabbit
• 결합: unconjugated
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 형태: buffered aqueous solution
• 분자량: ~68 kDa
• 종 반응성: human, mouse, rat
• 농도: 1 mg/mL
• 기술: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100; indirect immunofluorescence: 1:100-1:200; western blot: 1:500-1:1000
• 동형: IgG
• 면역원 서열: (P-V-T-P-T)
• NCBI 수납 번호: NP_001122092.1
• UniProt 수납 번호: Q13153
• 배송 상태: wet ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... PAK1(5058)

설명

면역원

Peptide sequence around aa. 210-214 (P-V-T-P-T), according to the protein PAK1.

특징 및 장점

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표적 설명

The activated kinase acts on a variety of targets. Likely to be the GTPase effector that links the Rho-related GTPases to the JNK MAP kinase pathway. Activated by CDC42 and RAC1. Involved in dissolution of stress fibers and reorganization of focal complexes. Involved in regulation of microtubule biogenesis through phosphorylation of TBCB. Activity is inhibited in cells undergoing apoptosis, potentially due to binding of CDC2L1 and CDC2L2.

물리적 형태

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable