SAB4200429

Anti-PIWIL4 antibody produced in rabbit

~1.0 mg/mL, affinity isolated antibody

• 동의어(들): Anti-HIWI2, Anti-MIWI2, Anti-Piwi-like 4
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• 결합: unconjugated
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 양식: buffered aqueous solution
• 분자량: antigen ~95 kDa
• 종 반응성: human
• 농도: ~1.0 mg/mL
• 기술: western blot: 0.5-1.0 μg/mL using lysates of HEK-293Tcells overexpressing human PIWIL4.
• UniProt 수납 번호: Q7Z3Z4
• 배송 상태: dry ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... PIWIL4(143689)

설명

일반 설명

P-element Induced WImpy testis (PIWI)-like 4 (PIWIL4) protein belongs to the PIWI subfamily. This protein is localized in tumorous colon tissues. PIWIL4 gene is located on the human chromosome at 11q21.

특이성

Anti-PIWIL4 recognizes human PIWIL4.

면역원

peptide corresponding to an internal region of human PIWIL4, conjugated to KLH. The corresponding sequence differs by a single amino acid in mouse and rat.

애플리케이션

Anti-PIWIL4 antibody produced in rabbit may be used in immunoblotting.

생화학적/생리학적 작용

P-element Induced WImpy testis (PIWI)-like 4 (PIWIL4) protein promotes tumorigenesis and cell invasion. It is expressed in several cancers like colon and breast cancer. This protein enhances cell growth and blocks apoptosis in cervical cancer cells. PIWIL4 protein is also involved in the chromatin-modifying pathway of human somatic cells. Mutation in the PIWIL4 gene is associated with breast cancer.

물리적 형태

Solution in 0.01 M phos­phate buffered saline, pH 7.4, containing 15 mM sodium azide.

저장 및 안정성

For continuous use, store at 2-8 °C for up to one month. For extended storage, freeze in working aliquots. Repeated freezing and thawing, or storage in “frost-free” freezers,is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilutions should be discarded if not used within 12 hours.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable