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Merck
모든 사진(1)

주요 문서

SAB4100327

Sigma-Aldrich

Monoclonal Anti-ADIPOQ antibody produced in mouse

clone ADIPOQ-A277, culture supernatant

동의어(들):

Anti-ACDC, Anti-ACRP30, Anti-ADIPQTL1, Anti-ADPN, Anti-APM-1, Anti-APM1, Anti-Adiponectin, C1Q and collagen domain containing, Anti-GBP28

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About This Item

UNSPSC 코드:
12352203
NACRES:
NA.41

결합

unconjugated

항체 형태

culture supernatant

항체 생산 유형

primary antibodies

클론

ADIPOQ-A277, monoclonal

양식

aqueous solution

분자량

antigen predicted mol wt 24.9 kDa

종 반응성

human

기술

western blot: suitable

동형

IgG1

UniProt 수납 번호

배송 상태

dry ice

저장 온도

−20°C

유전자 정보

human ... ADIPOQ(9370)

일반 설명

Adiponectin (ADIPOQ) gene is mapped to human chromosome 3q27.3. The gene codes for a 244 amino acid protein with four distinct regions. ADIPOQ is secreted by the adipocytes and is a most abundant circulating hormone.

면역원

ADIPOQ purified recombinant protein

생화학적/생리학적 작용

Adiponectin (ADIPOQ) is an adipocyte specific secreted protein that circulates in the plasma. The protein has a C-terminal globular domain and an NH2-terminal collagen domain. It has anti-atherosclerotic and anti-inflammatory properties. ADIPOQ has a role in physiological processes such as energy homeostasis and obesity. It exhibits anti-diabetic action by interacting with adiponectin receptors, AdipoR1 and AdipoR2. Low levels of adiponectin are also linked with hypertension and dyslipidemia. Mutation in the gene encoding it is linked with risk for endometrial cancer.

물리적 형태

Solution in Dulbecco′s Modified Eagle′s Medium with 10% fetal calf serum and 15 mM sodium azide.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Genetic architecture of the APM1 gene and its influence on adiponectin plasma levels and parameters of the metabolic syndrome in 1,727 healthy Caucasians
Heid IM, et al.
Diabetes, 55, 375-384 (2019)
Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome
Kadowaki T, et al.
The Journal of Clinical Investigation, 116, 1784-1792 (2019)
Plasma Concentrations of a Novel, Adipose-Specific Protein, Adiponectin, in Type 2 Diabetic Patients
Hotta K, et al.
Arteriosclerosis, Thrombosis, and Vascular Biology (2000)
In silico Evaluation of Nonsynonymous Single Nucleotide Polymorphisms in the ADIPOQ Gene Associated with Diabetes, Obesity, and Inflammation
Swamy AN, et al.
Avicenna Journal of Medical Biotechnology, 7(6), 121-121 (2015)
Association Between Single Nucleotide Polymorphism +276G T (rs1501299) in ADIPOQ and Endometrial Cancer
Bienkiewicz J, et al.
Pathology Oncology Research, 22, 135-138 (2019)

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