SAB3300047

Monoclonal Anti-TUBB3 antibody produced in mouse

clone 5H2, purified immunoglobulin, buffered aqueous glycerol solution

• 동의어(들): Anti-β-4, Anti-MC1R, Anti-TUBB4
• UNSPSC 코드: 12352203

속성

• 생물학적 소스: mouse
• 결합: unconjugated
• 항체 형태: purified immunoglobulin
• 항체 생산 유형: primary antibodies
• 클론: 5H2, monoclonal
• 형태: buffered aqueous glycerol solution
• 분자량: antigen 50.3 kDa
• 종 반응성: human
• 기술: western blot: suitable
• NCBI 수납 번호: NM_006086
• UniProt 수납 번호: Q13509
• 배송 상태: dry ice
• 저장 온도: −20°C
• 유전자 정보: human ... TUBB3(10381)

설명

면역원

Recombinant protein expressed in E. coli corresponding to amino acids 1-150 of human TUBB3

표적 설명

Tubulin is the major building block of microtubules. This intracellular cylindrical filamentous structure is present in almost all eukaryotic cells. Microtubules function as structural and mobile elements in mitosis, intracellular transport, flagellar movement, and the cytoskeleton. Except in the simplest eukaryotes, tubulin exists in all cells as a mixture of similar, but not identical, sets of alpha and beta tubulin polypeptides. Within either set of polypeptides, individual subunits diverge from each other (both within and across species) at less than 10% of the amino acid positions. The most extreme diversity is localized to the 15 residues of the carboxy terminal. For β-tubulin five evolutionarily conserved isotype clones have been identified. These are almost totally conserved in the subunits utilized in the same cell types of different species, with the exception of the hematopoietic β-tubulin which is the most highly divergent in sequence and is not conserved between species. Research has been centered around the hypothesis that these beta tubulin isotypes contribute to unique functional properties. It has been reported that the different isotypes of tubulin differ from each other in their ability to polymerize into microtubules.

물리적 형태

Solution in phosphate buffered saline containing 1% bovine serum albumin, 50% glycerol, and 0.02% sodium azide.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable