SAB2702324

Monoclonal Anti-CARD12 antibody produced in mouse

clone GT1387, affinity isolated antibody

• 동의어(들): AIFEC, CARD12, CLAN, CLAN1
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: mouse
• Quality Level: 100
• 결합: unconjugated
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: GT1387, monoclonal
• 형태: buffered aqueous solution
• 분자량: 116kDa
• 종 반응성: human
• 농도: 1mg/mL
• 기술: western blot: 1:1000-1:10000
• 동형: IgG2a
• UniProt 수납 번호: Q9NPP4
• 배송 상태: wet ice
• 저장 온도: −20°C
• 유전자 정보: human ... NLRC4(58484)

설명

면역원

Recombinant protein encompassing a sequence within the N-terminus region of human CARD12.

애플리케이션

Suggested starting dilutions are as follows: WB: 1:1000-1:10000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.

생화학적/생리학적 작용

In C. elegans, Ced4 binds and activates Ced3, an apoptotic initiator caspase, via caspase-associated recruitment domains (CARDs). Human Ced4 homologs include APAF1 (MIM 602233), NOD1/CARD4 (MIM 605980), and NOD2/CARD15 (MIM 605956). These proteins have at least 1 N-terminal CARD domain followed by a centrally located nucleotide-binding domain (NBD or NACHT) and a C-terminal regulatory domain, found only in mammals, that contains either WD40 repeats or leucine-rich repeats (LRRs). CARD12 is a member of the Ced4 family and can induce apoptosis.[supplied by OMIM]

특징 및 장점

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

기타 정보

Purification: Affinity purified by Protein A

물리적 형태

Phosphate-buffered saline, no preservative added.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable