SAB2701455

Anti-DYNC1LI1 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• 동의어(들): DNCLI1, DYNC1LI1, FLJ10219
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• 결합: unconjugated
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 양식: buffered aqueous solution
• 종 반응성: human, rat, mouse
• 기술: immunohistochemistry: suitable; immunoprecipitation (IP): suitable; indirect immunofluorescence: suitable; western blot: 1000-10000
• NCBI 수납 번호: AAI31621
• UniProt 수납 번호: Q9Y6G9
• 배송 상태: wet ice
• 저장 온도: −20°C
• 유전자 정보: human ... DYNC1LI1(51143)

설명

면역원

Recombinant fragment corresponding to a region within amino acids 318 and 523 of DYNC1LI1 according to AAI31621

애플리케이션

Suggested starting dilutions are as follows: ICC/IF: 1:100-1:1000, IHC-P: 1:100-1:1000, IP: 1:100-1:500, WB: 1:1000-1:10000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.

생화학적/생리학적 작용

Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. Probably involved in the microtubule-dependent transport of pericentrin. Is required for progress throuh the spindle assembly checkpoint. The phosphorylated form appears to be involved in the selective removal of MAD1L1 and MAD1L2 but not BUB1B from kinetochores.

특징 및 장점

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

물리적 형태

0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

면책조항

For U.S. Customers: Contains mercury; Do not place in trash - dispose according to local, state, or federal laws.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable