추천 제품
생물학적 소스
goat
결합
unconjugated
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
polyclonal
형태
buffered aqueous solution
종 반응성
human
기술
indirect ELISA: suitable
western blot: suitable
UniProt 수납 번호
배송 상태
dry ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... LAT(27040)
일반 설명
Linker for activation of T1 (LAT1) is a tyrosine-phosphorylated integral membrane protein. It is encoded by the gene mapped to human chromosome 16p11.2. LAT is found in peripheral blood lymphocytes, spleen, and thymus. In addition, its expression is also observed in various blood cell types including platelets, megakaryocytes, mast cells, and natural killer cells.
면역원
Peptide with sequence C-GAPDYENLQELN from the C Terminus of the protein sequence according to NP_055202.1; NP_001014987.1; NP_001014989.1; NP_001014988.1.
생화학적/생리학적 작용
Linker for activation of T1 (LAT1) protein is a transmembrane adaptor signaling molecule. It aids in connecting T cell antigen receptor complex (TCR) to intracellular signaling cascades, which is essential for T-cell development and function. Mutation in the LAT1 gene causes severe combined immunodeficiency (SCID).
특징 및 장점
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
물리적 형태
Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
C Windpassinger et al.
Cytogenetic and genome research, 97(3-4), 155-157 (2002-11-20)
We have mapped the LAT gene by radiation hybrid mapping and fluorescence in situ hybridization to chromosome 16p11.2. The complete cDNA sequence of LAT was generated using assembled sequences of cDNA fragments already available. BLAST analysis using the cDNA sequence
Chiara Bacchelli et al.
The Journal of allergy and clinical immunology, 139(2), 634-642 (2016-08-16)
Signaling through the T-cell receptor (TCR) is critical for T-cell development and function. Linker for activation of T cells (LAT) is a transmembrane adaptor signaling molecule that is part of the TCR complex and essential for T-cell development, as demonstrated by
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