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Merck
모든 사진(3)

문서

SAB2500485

Sigma-Aldrich

Anti-GPX3 antibody produced in goat

affinity isolated antibody, buffered aqueous solution

동의어(들):

Anti-Extracellular glutathione peroxidase, Anti-GPx-P, Anti-GSHPx-3, Anti-GSHPx-P, Anti-Glutathione peroxidase 3 (plasma)

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About This Item

UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

goat

결합

unconjugated

항체 형태

affinity isolated antibody

항체 생산 유형

primary antibodies

클론

polyclonal

형태

buffered aqueous solution

종 반응성

mouse, canine, rat, human

기술

immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable

UniProt 수납 번호

배송 상태

dry ice

저장 온도

−20°C

타겟 번역 후 변형

unmodified

유전자 정보

human ... GPX3(2878)

일반 설명

Glutathione peroxidase 3 (GPX3) belongs to the glutathione peroxidase (GPX) family. It is located on human chromosome 5q23.

면역원

Peptide with sequence C-NQFGKQEPGENSE from the internal region of the protein sequence according to NP_002075.2.

애플리케이션

Anti-GPX3 antibody has been used in western blotting.

생화학적/생리학적 작용

Glutathione peroxidase 3 (GPX3) blocks oxidative damages by decreasing redundant reactive oxygen species (ROS). It plays a major role in solid tumors and hematological malignancies. GPX3 also plays an important role in the effectiveness of leukemic stem cells (LSCs) and self renewal actions of hematopoietic stem cells (HSCs).

특징 및 장점

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

물리적 형태

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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문서 라이브러리 방문

Relationship between proinflammatory and antioxidant proteins with the severity of cardiovascular disease in type 2 diabetes mellitus
B G Fontana, et al.
International Journal of Molecular Sciences, 16(5), 9469-9483 (2015)
GPX3 methylation in bone marrow predicts adverse prognosis and leukemia transformation in myelodysplastic syndrome
J D Zhou, et al.
Cancer Medicine, 6(1), 267-274 (2017)
Beatriz García-Fontana et al.
International journal of molecular sciences, 16(5), 9469-9483 (2015-04-30)
Type 2 diabetes mellitus patients are at significant risk of cardiovascular disease, however, the pathophysiology of these complications is complex and incompletely known in this population. The aim of this study was to compare the serum proteome of patients with

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