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Merck
모든 사진(1)

문서

SAB2500273

Sigma-Aldrich

Anti-CRHR1/CRF-R (AA 250-263) antibody produced in goat

affinity isolated antibody, buffered aqueous solution

동의어(들):

Anti-CRF-R, Anti-CRF1, Anti-CRH-R1h, Anti-Corticotropin releasing hormone receptor 1

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About This Item

UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

goat

결합

unconjugated

항체 형태

affinity isolated antibody

항체 생산 유형

primary antibodies

클론

polyclonal

형태

buffered aqueous solution

종 반응성

human

기술

immunohistochemistry: suitable
indirect ELISA: suitable
indirect immunofluorescence: suitable

UniProt 수납 번호

배송 상태

dry ice

저장 온도

−20°C

타겟 번역 후 변형

unmodified

유전자 정보

human ... CRHR1(1394)

일반 설명

Corticotropin releasing factor receptor 1 (CRHR1) belongs to the G-protein-coupled receptor superfamily of brain-gut neuropeptides. It is highly expressed in the amygdala, hippocampus and frontal cortex. The gene encoding CRHR1 consists of 13 exons and is localized on human chromosome 17q12-q22.

면역원

Peptide with sequence KLYYDNEKCWFGKR from the internal region of the protein sequence according to NP_004373.2.

생화학적/생리학적 작용

Corticotropin releasing factor receptor 1 (CRHR1) helps to initiate signal transduction pathways that control various functions like stress, reproduction, immune response and obesity. It blocks the multiplication of endocrine-related cancer cell lines.

특징 및 장점

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

물리적 형태

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

예방조치 성명서

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리 방문

Urocortinergic system in the testes of normal and cryptorchid dogs
Caterina Squillacioti
Annals of Anatomy = Anatomischer Anzeiger : Official Organ of the Anatomische Gesellschaft, 207 (2016)
Association analysis of polymorphisms of the CRHR1 gene with infantile spasms
Guang Yang
Molecular Medicine Reports (2015)
The activation of type 1 corticotropin releasing factor receptor (CRF-R1) inhibits proliferation and promotes differentiation of neuroblastoma cells in vitro via p27(Kip1) protein up-regulation and c-Myc mRNA down-regulation.
Pozzoli G
Molecular and Cellular Endocrinology (2015)
Family Economic Hardship, Corticotropin-Releasing Hormone Receptor Polymorphisms, and Depressive Symptoms in Rural African American Youths
Yi-fu Chen
The Journal of Adolescent Health : Official Publication of the Society for Adolescent Medicine (2015)

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