SAB1403982

Monoclonal Anti-INS antibody produced in mouse

clone 7C8, purified immunoglobulin, buffered aqueous solution

• 동의어(들): ILPR, IRDN
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: mouse
• 결합: unconjugated
• 항체 형태: purified immunoglobulin
• 항체 생산 유형: primary antibodies
• 클론: 7C8, monoclonal
• 형태: buffered aqueous solution
• 분자량: antigen ~1.65 kDa
• 종 반응성: human
• 기술: indirect ELISA: suitable
• 동형: IgG3κ
• NCBI 수납 번호: NM_000207
• UniProt 수납 번호: P01308
• 배송 상태: dry ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... INS(3630)

설명

일반 설명

After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into two chains (peptide A and peptide B) that are covalently linked via two disulfide bonds. Binding of this mature form of insulin to the insulin receptor (INSR) stimulates glucose uptake. A variety of mutant alleles with changes in the coding region have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5′ region and with the IGF2 gene at the 3′ region. (provided by RefSeq)

면역원

KLH-conjugated human Proinsulin peptide (NP_000198, 48 a.a. ~ 62 a.a)

Sequence
CFFYTPKTRREAEDLQ

물리적 형태

Solution in phosphate buffered saline, pH 7.4

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable