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Merck
모든 사진(2)

문서

S8753

Sigma-Aldrich

Strychnine hydrochloride

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모든 사진(2)

About This Item

실험식(Hill 표기법):
C21H22N2O2 · HCl
CAS Number:
1421-86-9
Molecular Weight:
370.87
EC Number:
215-826-9
MDL number:
MFCD00058174
UNSPSC 코드:
12352210
PubChem Substance ID:
24899812
NACRES:
NA.32

SMILES string

Cl.[H][C@@]12CC(=O)N3c4ccccc4[C@]56CCN7CC(=CCO1)[C@]([H])(C[C@@]57[H])[C@]2([H])[C@]36[H]

InChI

1S/C21H22N2O2.ClH/c24-18-10-16-19-13-9-17-21(6-7-22(17)11-12(13)5-8-25-16)14-3-1-2-4-15(14)23(18)20(19)21;/h1-5,13,16-17,19-20H,6-11H2;1H/t13-,16-,17-,19-,20-,21+;/m0./s1

InChI key

VLXYTKMPCOQKEM-ZEYGOCRCSA-N

유사한 제품을 찾으십니까? 방문 제품 비교 안내

애플리케이션

Strychnine hydrochloride has been used as a glycine receptor antagonist in the retina for biophysiological functions. It has also been used to block glutamatergic, GABAergic and glycinergic receptors and gap junctions.

생화학적/생리학적 작용

Strychnine is a potent convulsant, which is extracted from Strychnos nux vomica seeds. At high doses, the compound causes convulsions and ultimately death due to respiratory paralysis. Strychnine acts as a respiratory, circulatory and digestive stimulant.
Convulsant; glycine receptor antagonist not associated with the NMDA receptor.

픽토그램

Skull and crossbonesEnvironment
GHS06,GHS09

신호어

Danger

유해 및 위험 성명서

H300 + H330,H410

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

시험 성적서(COA)

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문서 라이브러리 방문

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D-(+)-Trehalose dihydrate ≥98.5% (HPLC), from Saccharomyces cerevisiae

Sigma-Aldrich

T5251

D-(+)-Trehalose dihydrate

TES ≥99% (titration)

Sigma-Aldrich

T1375

TES

Chlorpromazine hydrochloride ≥98% (TLC)

Sigma-Aldrich

C8138

Chlorpromazine hydrochloride

Strychnos nux-vomica seeds: Pharmacognostical standardization, extraction, and antidiabetic activity
Bhati R, et al.
Journal of Ayurveda and integrative medicine, 3(2), 80-80 (2012)
Shankai Yin et al.
Hearing research, 237(1-2), 32-48 (2008-02-08)
Neural tuning to sound durations is a useful filter for the identification of a variety of sounds. Previous studies have shown that the interaction between excitatory and inhibitory inputs plays a role in duration selectivity in echolocating bats. However, this
Biomarkers in Toxicology null
Daniel S Borrus et al.
eNeuro, 7(3) (2020-05-13)
The preBötzinger complex (preBötC) gives rise to two types of breathing behavior under normal physiological conditions: eupnea and sighing. Here, we examine the neural mechanisms that couple their underlying rhythms. We measured breathing in awake intact adult mice and recorded
Effect of Strychinine, a Glycine Inhibitor, on the Programmed Cell Death of Motoneurons during the Chick Development.
Kim JY
Experimental Neurobiology, 20(4), 176-180 (2011)
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