추천 제품
분석
~85%
양식
powder
색상
yellow to greenish yellow
항생제 활성 스펙트럼
neoplastics
동작 모드
enzyme | interferes
SMILES string
CC(=O)Nc1ccc(cc1)S(=O)(=O)Nc2ccc(cc2)[N+]([O-])=O
InChI
1S/C14H13N3O5S/c1-10(18)15-11-4-8-14(9-5-11)23(21,22)16-12-2-6-13(7-3-12)17(19)20/h2-9,16H,1H3,(H,15,18)
InChI key
GWBPFRGXNGPPMF-UHFFFAOYSA-N
유사한 제품을 찾으십니까? 방문 제품 비교 안내
애플리케이션
Sulfanitran is used to stimulate MRP2. It is used to stimulate the MRP2-mediated transport of lipophilic amphipathic drugs. It is used to study the efflux of chemotherapeutics in tumor cell lines.
생화학적/생리학적 작용
Sulfanitran stimulates the ATP binding cassette family transporter multidrug resistance protein 2 (MRP2). Sulfanitran increases the affinity of MRP2 for estradiol-17-β-D-glucuronide. It stimulates the vectorial transport of saquinavir, a MRP2 substrate, across polarized MDCKII monolayers.
기타 정보
Keep container tightly closed in a dry and well-ventilated place.
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
가장 최신 버전 중 하나를 선택하세요:
Jurjen S Lagas et al.
Drug metabolism and disposition: the biological fate of chemicals, 37(1), 129-136 (2008-10-11)
Diclofenac is an important analgesic and anti-inflammatory drug, widely used for treatment of postoperative pain, rheumatoid arthritis, and chronic pain associated with cancer. Consequently, diclofenac is often used in combination regimens and undesirable drug-drug interactions may occur. Because many drug-drug
Noam Zelcer et al.
The Journal of biological chemistry, 278(26), 23538-23544 (2003-04-19)
Multidrug resistance protein 2 (MRP2) belongs to the ATP binding cassette family of transporters. Its substrates include organic anions and anticancer drugs. We have used transport assays with vesicles derived from Sf9 insect cells overproducing MRP2 to study the interactions
Darko Ursic et al.
International journal of pharmaceutics, 381(2), 199-204 (2009-09-29)
Intestinal efflux transporters can significantly reduce the absorption of the drug after peroral application. In this work we studied secretion of glutathione conjugates triggered by glucose at the luminal side of the intestine. Glucose stimulated secretion of DNPSG, NEMSG and
Hehui Zheng et al.
Se pu = Chinese journal of chromatography, 25(2), 238-240 (2007-06-22)
A method for the determination of 12 sulfonamides (SAs) (sulfanilamide, sulfamonomethoxine, sulfacetamide, sulfamethoxazole, sulfadiazine, sulfisoxazole, sulfathiazole, sulfadi-methoxine, sulfamerazine, sulfaquinoxaline, sulfamethazine, sulfanitran) in cosmetics was developed by ultra performance liquid chromatography with photodiode array detector (UPLC-PDA). The chromatographic column used was
Marilyn J Schneider et al.
Analytical and bioanalytical chemistry, 407(15), 4423-4435 (2014-12-30)
Multiclass, multiresidue methods are becoming increasingly popular in regulatory monitoring programs due to their increased analytical scope and laboratory efficiency. In this work, we report the development and validation of a new high-throughput analytical method to monitor up to 131
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