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Merck
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문서

RAB0393

Sigma-Aldrich

Human Oncostatin M (OSM) ELISA Kit

for serum, plasma, cell culture supernatants and urine

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모든 사진(2)

About This Item

UNSPSC 코드:
41116158
NACRES:
NA.32

종 반응성

human

포장

kit of 96 wells (12 strips x 8 wells)

기술

ELISA: suitable
capture ELISA: suitable

입력

sample type urine
sample type plasma
sample type cell culture supernatant(s)
sample type serum

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 1 pg/mL
standard curve range: 1.37-1000 pg/mL

검출 방법

colorimetric

배송 상태

wet ice

저장 온도

−20°C

유전자 정보

human ... OSM(5008)

관련 카테고리

일반 설명

Oncostatin M (OSM) is a multifunctional hematopoietic cytokine that belongs to the interleukin-6 (IL-6) cytokine family. Human OSM is produced by activated T lymphocytes and monocytes mainly during inflammatory disorders. OSM acts as a cell growth modulator. In addition, it also participates in low-density lipoprotein (LDL) receptor upregulation and induction of hematopoietic factors. OSM contributes to the inflammatory process, autoimmunity, and immunopathogenesis of cancers.

면역원

Recombinant Human OSM

애플리케이션

The Human Oncostatin M (OSM) ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human Oncostatin M in serum, plasma, cell culture supernatants, and urine.

기타 정보

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

키트 구성품 역시 별도로 이용 가능함

제품 번호
설명
SDS
  • RABELADAELISA 1X Assay/Sample Diluent Buffer A (Item D1)SDS
  • RABELADBELISA 5X Assay/Sample Diluent Buffer B (Item E1)SDS
  • RABSTOP3ELISA Stop Solution (Item I)SDS
  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)SDS
  • RABWASH420X Wash Buffer (Item B)SDS

픽토그램

Corrosion
GHS05

신호어

Warning

유해 및 위험 성명서

H290

예방조치 성명서

P234 - P390

Hazard Classifications

Met. Corr. 1

Storage Class Code

8A - Combustible corrosive hazardous materials

시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리 방문

A Grenier et al.
Blood, 93(4), 1413-1421 (1999-02-09)
Oncostatin M (OSM) is an interleukin-6 (IL-6) family cytokine known in particular to induce the synthesis of acute-phase proteins by hepatocytes. Because human polymorphonuclear neutrophils (PMN) can secrete numerous cytokines, the potential production of OSM by PMN was investigated. Highly
Pulmonary expression of oncostatin M (OSM) promotes inducible BALT formation independently of IL-6, despite a role for IL-6 in OSM-driven pulmonary inflammation.
Botelho FM
Journal of Immunology, 191, 1453-1464 (2013)
Y Ma et al.
Nucleic acids research, 27(23), 4649-4657 (1999-11-11)
Oncostatin M (OSM), an IL-6 subfamily cytokine, inhibits proliferation and causes morphological changes in many tumor cell lines. GM-CSF, phorbol-12-myristate-13-acetate (PMA), and lipopolysaccharide (LPS) induce OSM expression. To investigate the mechanisms governing OSM promoter activity, we have cloned and partially
Oncostatin M: A mysterious cytokine in cancers.
Masjedi, et al.
International Immunopharmacology, 90, 107158-107158 (2021)

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