Q3638

Quetiapine hemifumarate salt

≥98% (HPLC)

• 동의어(들): 2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol hemifumarate, Quetiapine fumarate
• 실험식(Hill 표기법): C₂₁H₂₅N₃O₂S · 0.5C₄H₄O₄
• CAS Number: 111974-72-2
• Molecular Weight: 441.54
• MDL number: MFCD03423782
• UNSPSC 코드: 12352200
• PubChem Substance ID: 329823864
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 형태: powder
• 저장 조건: desiccated
• 색상: white to off-white
• solubility: DMSO: >10 mg/mL
• 주관자: AstraZeneca
• 저장 온도: 2-8°C
• SMILES string: OC(=O)\C=C\C(O)=O.OCCOCCN1CCN(CC1)C2=Nc3ccccc3Sc4ccccc24.OCCOCCN5CCN(CC5)C6=Nc7ccccc7Sc8ccccc68
• InChI: 1S/2C21H25N3O2S.C4H4O4/c2*25-14-16-26-15-13-23-9-11-24(12-10-23)21-17-5-1-3-7-19(17)27-20-8-4-2-6-18(20)22-21;5-3(6)1-2-4(7)8/h2*1-8,25H,9-16H2;1-2H,(H,5,6)(H,7,8)/b;;2-1+
• InChI key: ZTHJULTYCAQOIJ-WXXKFALUSA-N
• 유전자 정보: human ... DRD2(1813) , HTR2A(3356) , HTR2C(3358)

설명

일반 설명

Quetiapine is a derivative of dibenzothiazepine compound and is also referred to as seroquel and clemastine.

애플리케이션

Quetiapine hemifumarate salt has been used as an antagonist for β-arrestin 2 mutant T205M recruitment.

생화학적/생리학적 작용

Quetiapine hemifumarate is an atypical antipsychotic, a combined serotonin (5HT2) and dopamine (D2) receptor antagonist.

Quetiapine promotes oligodendrogenesis in vitro. It is used in treating depressive disorders.

특징 및 장점

This compound is featured on the Dopamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by AstraZeneca. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

안전성 정보

• 픽토그램: GHS07,GHS09
• 신호어: Warning
• 유해 및 위험 성명서: H302,H400
• 예방조치 성명서: P273 - P301 + P312 + P330
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Acute 1
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable