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Merck
모든 사진(1)

주요 문서

Q110

Sigma-Aldrich

Quinelorane dihydrochloride

crystalline

동의어(들):

(5aR-trans)-5,5a,6,7,8,9,9a,10-Octahydro-6-propylpyrido[2,3-g]quinazolin-2-amine dihydrochloride, LY-163,502

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About This Item

실험식(Hill 표기법):
C14H22N4 · 2HCl
CAS Number:
Molecular Weight:
319.27
MDL number:
UNSPSC 코드:
12352200
PubChem Substance ID:

양식

crystalline

색상

white

solubility

H2O: >10 mg/mL

SMILES string

Cl.Cl.[H][C@]12CCCN(CCC)[C@]1([H])Cc3cnc(N)nc3C2

InChI

1S/C14H22N4.2ClH/c1-2-5-18-6-3-4-10-7-12-11(8-13(10)18)9-16-14(15)17-12;;/h9-10,13H,2-8H2,1H3,(H2,15,16,17);2*1H/t10-,13-;;/m1../s1

InChI key

WDEMLQIGYYLRRX-OWVUFADGSA-N

유전자 정보

human ... DRD2(1813)

생화학적/생리학적 작용

D2 dopamine receptor agonist; 2-aminopyridine analog of quinpirole.

법적 정보

Manufactured and sold with the permission of Eli Lilly and Company.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

J H Carlson et al.
Synapse (New York, N.Y.), 11(3), 229-248 (1992-07-01)
The rates and patterns of discharge activity exhibited by 16 spontaneously active substantia nigra pars compacta dopamine neurons were studied in halothane-anesthetized rats using three types of quantitative measures: 1) mean discharge rates, 2) population characteristics of interspike interval samples
M J Eaton et al.
The Journal of pharmacology and experimental therapeutics, 268(2), 645-652 (1994-02-01)
The purpose of the present study was to characterize dopaminergic D2 receptor-mediated regulation of catecholaminergic neurons in the diencephalon by examining the acute effects of the potent and selective D2 agonist quinelorane (LY163502; trans-(-)-5,5a,6,7,8,9,9a,10-octahydro-6-propylpyrimido [4,5-g] quinolin-2-amine dihydrochloride dihydrate) on concentrations
M A Charles et al.
Pharmacology, biochemistry, and behavior, 43(4), 1087-1092 (1992-12-01)
LY163502, a selective D2 receptor agonist, has been reported to stimulate sexual behavior in both copulating and noncopulating male rats. Three experiments were conducted to further characterize the role of dopamine on male sexual behavior. In the first experiment, quinelorane

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