PZ0205

CE-178253 benzenesulfonate salt

≥98% (HPLC)

• 동의어(들): 1-[7-(2-Chlorophenyl)-8-(4-chlorophenyl)-2-methylpyrazolo[1,5-a]-1,3,5-triazin-4-yl]-3-(ethylamino)-3-azetidinecarboxamide benzenesulfonate salt
• 실험식(Hill 표기법): C₂₄H₂₃Cl₂N₇O · C₆H₆O₃S
• CAS Number: 956246-95-0
• Molecular Weight: 654.57
• MDL number: MFCD22666387
• UNSPSC 코드: 51111800
• PubChem Substance ID: 329823773
• NACRES: NA.77

속성

• 분석: ≥98% (HPLC)
• 형태: powder
• 색상: white to beige
• solubility: DMSO: 10 mg/mL (clear solution)
• 저장 온도: room temp
• SMILES string: OS(=O)(=O)c1ccccc1.CCNC2(CN(C2)c3nc(C)nc4c(-c5ccc(Cl)cc5)c(nn34)-c6ccccc6Cl)C(N)=O
• InChI: 1S/C24H23Cl2N7O.C6H6O3S/c1-3-28-24(22(27)34)12-32(13-24)23-30-14(2)29-21-19(15-8-10-16(25)11-9-15)20(31-33(21)23)17-6-4-5-7-18(17)26;7-10(8,9)6-4-2-1-3-5-6/h4-11,28H,3,12-13H2,1-2H3,(H2,27,34);1-5H,(H,7,8,9)
• InChI key: PUVYOZFJBITEFT-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

CE-178253 is an extremely potent and selective CB1 antagonist with sub-nanomolar potency. In binding assays, CE-178253 has a 0.33 nM Ki for human CB1, vs. a Ki of > 10 mM for human CB2.

특징 및 장점

This compound is featured on the Cannabinoid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

안전성 정보

• 픽토그램: GHS06
• 신호어: Danger
• 유해 및 위험 성명서: H301
• 예방조치 성명서: P264 - P270 - P301 + P310 - P405 - P501
• Hazard Classifications: Acute Tox. 3 Oral
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable