모든 사진(1)

문서

PZ0180

Delavirdine mesylate

Name: Delavirdine mesylate
Brand: SIGMA

≥98% (HPLC)

동의어(들):

N-[2-[[4-[3-[(1-Methylethyl)amino]-2-pyridinyl]-1-piperazinyl]carbonyl]-1H-indol-5-yl]methanesulfonamide mesylate, Rescriptor

로그인조직 및 계약 가격 보기

모든 사진(1)

About This Item

실험식(Hill 표기법):

C₂₂H₂₈N₆O₃S · CH₃SO₃H

CAS Number:

147221-93-0

Molecular Weight:

552.67

MDL number:

MFCD00866948

UNSPSC 코드:

51111800

PubChem Substance ID:

329823754

NACRES:

NA.77

추천 제품

Slide 1 of 10

1 of 10

Sigma-Aldrich

D2650

Dimethyl sulfoxide

Sigma-Aldrich

H9523

Serotonin hydrochloride

Sigma-Aldrich

S4568

SCH 58261

Sigma-Aldrich

A7007

S-(5′-Adenosyl)-L-methionine chloride dihydrochloride

Supelco

PHR1396

Methotrexate

Sigma-Aldrich

M4287

Mitomycin C from Streptomyces caespitosus

Sigma-Aldrich

T0254

L-Tryptophan

Supelco

PHR1771

Digoxin

Sigma-Aldrich

SML1221

Dutasteride

Supelco

14927

Serotonin

분석

≥98% (HPLC)

형태

powder

색상

white to tan

mp

315 °C

solubility

DMSO: >5 mg/mL

저장 온도

room temp

SMILES string

CS(O)(=O)=O.CC(C)Nc1cccnc1N2CCN(CC2)C(=O)c3cc4cc(NS(C)(=O)=O)ccc4[nH]3

InChI

1S/C22H28N6O3S.CH4O3S/c1-15(2)24-19-5-4-8-23-21(19)27-9-11-28(12-10-27)22(29)20-14-16-13-17(26-32(3,30)31)6-7-18(16)25-20;1-5(2,3)4/h4-8,13-15,24-26H,9-12H2,1-3H3;1H3,(H,2,3,4)

InChI key

MEPNHSOMXMALDZ-UHFFFAOYSA-N

생화학적/생리학적 작용

Delavirdine is a non-nucleoside reverse transcriptase inhibitor (NNRTI). It is used as part of highly active antiretroviral therapy (HAART) for the treatment of human immunodeficiency virus (HIV) type 1.

특징 및 장점

This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Addressing ceiling effects in health status measures: a comparison of techniques applied to measures for people with HIV disease.

I-Chan Huang et al.

Health services research, 43(1 Pt 1), 327-339 (2008-01-24)

To compare different approaches to address ceiling effects when predicting EQ-5D index scores from the 10 subscales of the MOS-HIV Health Survey. Data were collected from an HIV treatment trial. Statistical methods included ordinary least squares (OLS) regression, the censored

US and UK versions of the EQ-5D preference weights: does choice of preference weights make a difference?

I-Chan Huang et al.

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 16(6), 1065-1072 (2007-04-07)

Most US studies that estimate EQ-5D index score generally apply the UK preference weights. We compared the validity of a newly-developed US weights to the UK weights for use of EQ-5D as a measure of health-related quality of life. Data

Biosensor-based kinetic characterization of the interaction between HIV-1 reverse transcriptase and non-nucleoside inhibitors.

Matthis Geitmann et al.

Journal of medicinal chemistry, 49(8), 2367-2374 (2006-04-14)

Details of the interaction between HIV-1 reverse transcriptase and non-nucleoside inhibitors (NNRTIs) have been elucidated using a biosensor-based approach. This initial study was performed with HIV-1 reverse transcriptase mutant K103N, the phenethylthioazolylthiourea compound (PETT) MIV-150, and the three NNRTIs licensed

Human immunodeficiency virus type 1 resistance or cross-resistance to nonnucleoside reverse transcriptase inhibitors currently under development as microbicides.

Philippe Selhorst et al.

Antimicrobial agents and chemotherapy, 55(4), 1403-1413 (2011-02-02)

Microbicides based on nonnucleoside reverse transcriptase inhibitors (NNRTIs) are currently being developed to protect women from HIV acquisition through sexual contact. However, the large-scale introduction of these products raises two major concerns. First, when these microbicides are used by undiagnosed

The human immunodeficiency virus type 1 nonnucleoside reverse transcriptase inhibitor resistance mutation I132M confers hypersensitivity to nucleoside analogs.

Zandrea Ambrose et al.

Journal of virology, 83(8), 3826-3833 (2009-02-06)

We previously identified a rare mutation in human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT), I132M, which confers high-level resistance to the nonnucleoside RT inhibitors (NNRTIs) nevirapine and delavirdine. In this study, we have further characterized the role of

모든 관련된 서류 보기

문서

면역학 연구를 위한 생체 활성 저분자

당사는 다양한 항생제, 항바이러스제, 항진균제와 더불어 면역체계 신호전달 표적 식별 및 검증을 위한 작용제, 길항제, 조절제 및 기타 생체 활성 저분자를 제공합니다.

Bioactive Molecules for Immunology Research

Bioactive small molecules for immune system signaling target identification/validation and antibiotics, antivirals, and antifungals offered.

Discover Bioactive Small Molecules for ADME/Tox

문서

Delavirdine mesylate

≥98% (HPLC)

About This Item

추천 제품

속성

분석

형태

색상

mp

solubility

저장 온도

SMILES string

InChI

InChI key

관련 카테고리

설명

생화학적/생리학적 작용

특징 및 장점

안전성 정보

Storage Class Code

WGK

Flash Point (°F)

Flash Point (°C)

문서

시험 성적서(COA)

이 제품을 이미 가지고 계십니까?

관련 참고 논문

관련 참고 프로토콜

문서

관련 콘텐츠

기술 서비스