Quality Level
분석
≥98% (HPLC)
양식
powder
광학 활성
[α]/D +100 to +120°, c = 0.025 mg/mL in methanol
색상
brown-red
solubility
DMSO: ≥5 mg/mL
저장 온도
room temp
SMILES string
CN1CCC[C@@H]1Cc2c[nH]c3ccc(Nc4ncccc4[N+]([O-])=O)cc23
InChI
1S/C19H21N5O2/c1-23-9-3-4-15(23)10-13-12-21-17-7-6-14(11-16(13)17)22-19-18(24(25)26)5-2-8-20-19/h2,5-8,11-12,15,21H,3-4,9-10H2,1H3,(H,20,22)/t15-/m1/s1
InChI key
YPFIYPNOWVPAPR-OAHLLOKOSA-N
생화학적/생리학적 작용
CP-135807 is a selective 5-HT1D agonist.
신호어
Warning
유해 및 위험 성명서
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
표적 기관
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
Journal of neurochemistry, 67(5), 2204-2207 (1996-11-01)
In vivo microdialysis in guinea pig hypothalamus was used to study the effect of serotonin [5-hydroxytryptamine (5-HT)] subtype 1D autoreceptor blockade on the increase in extracellular 5-HT levels produced by a selective 5-HT reuptake inhibitor (SSRI). Administration of the selective
European journal of pharmacology, 499(1-2), 67-75 (2004-09-15)
The in vitro pharmacological properties of AR-A000002 ((R)-N-[5-methyl-8-(4-methylpiperazin-1-yl)-1,2,3,4-tetrahydro-2-naphthyl]-4-morpholinobenzamide), a novel 5-hydroxytryptamine (5-HT)(1B) receptor antagonist, were studied. AR-A000002 bound with high affinity to guinea pig cortex and recombinant guinea pig 5-HT(1B) receptors (Ki=0.24 and 0.47 nM) and with 10-fold lower affinity
문서
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