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Merck
모든 사진(3)

Key Documents

PRS4553

Sigma-Aldrich

Anti-Unc93b antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

동의어(들):

Anti-Unc-93 homolog B1 (C. elegans), Anti-Unc93b1

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About This Item

UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

rabbit

Quality Level

결합

unconjugated

항체 형태

affinity isolated antibody

항체 생산 유형

primary antibodies

클론

polyclonal

형태

buffered aqueous solution

종 반응성

rat, human, mouse

기술

immunofluorescence: suitable
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable

UniProt 수납 번호

배송 상태

dry ice

저장 온도

−20°C

타겟 번역 후 변형

unmodified

유전자 정보

human ... UNC93B1(81622)

일반 설명

Unc93b (unc-93 homolog B1) is a multiple membrane-spanning protein, that is located in the endoplasmic reticulum. It is mainly present in the heart and also highly expressed in dendritic cells and macrophages. It is located on chromosome 11q13.

면역원

a 19 amino acid peptide from near the amino-terminus of human Unc93b.

생화학적/생리학적 작용

Unc93b (unc-93 homolog B1) plays an important role in controlling the activation of TLRs (toll-like receptors). It also participates in the localization of TLR3 (toll-like receptor 3) to the surface of cell.

결합

The action of this antibody can be blocked using blocking peptide SBP4553.

물리적 형태

Solution in phosphate buffered saline containing 0.02% sodium azide

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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관련 제품

제품 번호
설명
가격

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

hUNC-93B1, a novel gene mainly expressed in the heart, is related to left ventricular diastolic function, heart failure morbidity and mortality in elderly men
Arnlov J, et al.
European Journal of Heart Failure, 7(6), 958-965 (2005)
Unc93B1 biases Toll-like receptor responses to nucleic acid in dendritic cells toward DNA- but against RNA-sensing
Fukui R, et al.
The Journal of Experimental Medicine, 206(6), 1339-1350 (2009)
The role of UNC93B1 protein in surface localization of TLR3 receptor and in cell priming to nucleic acid agonists
Pohar J, et al.
The Journal of Biological Chemistry, 288(1), 442-454 (2013)
Assessing the function of human UNC-93B in Toll-like receptor signaling and major histocompatibility complex II response
Koehn J, et al.
Human immunology, 68(11), 871-878 (2007)
hUNC93B1: a novel human gene representing a new gene family and encoding an unc-93-like protein
Kashuba VI, et al.
Gene, 283(1-2), 209-217 (2002)

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