PLA0277

Rabbit anti-Cul1 Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

• 동의어(들): CUL-1, Protein YL-1
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 항체 형태: affinity purified immunoglobulin
• 항체 생산 유형: primary antibodies
• Grade: Powered by Bethyl Laboratories, Inc.
• 종 반응성: human, mouse
• 기술: immunoprecipitation (IP): 2-10 μg/mg; western blot: 1:2,000- 1:10,000
• 수납 번호(accession number): NP_003583.2
• UniProt 수납 번호: Q13616
• 배송 상태: wet ice
• 저장 온도: 2-8°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: rabbit ... Cul1(8454)

설명

면역원

The epitope recognized by PLA0277 maps to a region between residue 726 and 776 of human Cullin 1 using the numbering given in entry NP_003583.2 (GeneID 8454).

물리적 형태

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

기타 정보

Cullin 1 (Cul1) is the core component of multiple cullin-RING-based SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, Cul1 serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits. Cul1 may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q13616]

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: nwg
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable