P4532

(−)-N⁶-(2-Phenylisopropyl)adenosine

solid

• 동의어(들): (R)-N⁶-(1-Methyl-2-phenylethyl)adenosine, N⁶-(L-2-Phenylisopropyl)adenosine, R-(−)-PIA
• 실험식(Hill 표기법): C₁₉H₂₃N₅O₄
• CAS Number: 38594-96-6
• Molecular Weight: 385.42
• EC Number: 254-028-5
• MDL number: MFCD00069194
• UNSPSC 코드: 12352200
• PubChem Substance ID: 24277681
• NACRES: NA.77

속성

• 형태: solid
• Quality Level: 200
• 효능: 1.17 nM K_i for A₁ receptors (using [³H]CHA in rat forebrain preparations)
• 색상: white
• solubility: H₂O: slightly soluble 0.3 mg/mL (Solutions may be stored for several days at 4°C.); 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 1.6 mg/mL (Solutions may be stored for several days at 4°C.)
• 저장 온도: 2-8°C
• SMILES string: C[C@H](Cc1ccccc1)Nc2ncnc3n(cnc23)[C@@H]4O[C@H](CO)[C@@H](O)[C@H]4O
• InChI: 1S/C19H23N5O4/c1-11(7-12-5-3-2-4-6-12)23-17-14-18(21-9-20-17)24(10-22-14)19-16(27)15(26)13(8-25)28-19/h2-6,9-11,13,15-16,19,25-27H,7-8H2,1H3,(H,20,21,23)/t11-,13-,15-,16-,19-/m1/s1
• InChI key: RIRGCFBBHQEQQH-SSFGXONLSA-N
• 유전자 정보: human ... ADORA1(134)

설명

생화학적/생리학적 작용

A₁ adenosine receptor agonist. Affinity for adenosine receptor is approx. 100× that of the (+)-isomer.

특징 및 장점

This compound is featured on the Adenosine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)