P3493

Monoclonal Anti-Placenta Growth Factor-2 antibody produced in rat

clone 62526, purified immunoglobulin, lyophilized powder

• 동의어(들): Anti-PlGF-2
• MDL number: MFCD02097209
• UNSPSC 코드: 51111800
• NACRES: NA.41

속성

• 생물학적 소스: rat
• Quality Level: 100
• 결합: unconjugated
• 항체 형태: purified immunoglobulin
• 항체 생산 유형: primary antibodies
• 클론: 62526, monoclonal
• 형태: lyophilized powder
• 종 반응성: mouse
• 기술: indirect ELISA: 0.5-1.0 μg/mL; neutralization: suitable; western blot: 1-2 μg/mL
• 동형: IgG2a
• UniProt 수납 번호: P49764
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: mouse ... Pgf(18654)

설명

일반 설명

The antibody neutralizes receptor-ligand interaction. The antibody shows no cross-reactivity with recombinant human PlGF and recombinant human VEGF.

면역원

purified recombinant mouse placenta growth factor 2 expressed in insect Sf 21 cells.

생화학적/생리학적 작용

Placental growth factors (PlGF) are involved in the growth, migration and survival of endothelial cells. All the four isoforms identified are expressed in placenta and umbilical vein endothelial cells. PlGF bind to specific Flt-1 receptors that result in activation and recruitment of dendritic cells, smooth muscle cells and inflammatory cells. PlGF2 has the ability to bind heparin while PlGF1 is a soluble isoform.

물리적 형태

Lyophilized from a 0.2 μm filtered solution of phosphate buffered saline with 5% trehalose.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)